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          antidepressants

          This shows a brain.
          FeaturedNeurologyNeuroscience
          ·May 30, 2025·4 min read

          SSRIs Restore Brain Function in Alzheimer’s

          A new study suggests that SSRIs, commonly prescribed antidepressants, may reduce biological markers of Alzheimer’s disease. In a cohort of 191 individuals, AD patients on SSRIs had lower levels of plasma phosphorylated tau-181, a key indicator of disease severity.
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          This shows a brain.
          FeaturedNeurosciencePsychology
          ·May 24, 2025·4 min read

          Boosting Ketamine’s Antidepressant Effects to Last Two Months

          Ketamine is a fast-acting antidepressant that can relieve symptoms of major depressive disorder (MDD) within hours, even in treatment-resistant cases. However, its effects typically last only a week, and frequent dosing poses risks like dissociation or addiction.
          Read More
          This shows two heads and pills.
          Neuroscience
          ·May 22, 2025·6 min read

          Long-Term Antidepressant Use Tied to Tougher Withdrawal Symptoms

          A new study finds that people who have taken antidepressants for more than two years are significantly more likely to experience withdrawal symptoms when stopping the medication. The longer someone used antidepressants, the more severe and prolonged the symptoms became, with 64% of long-term users reporting moderate or severe withdrawal.
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          This shows a baby and a brain.
          FeaturedNeurosciencePsychology
          ·May 7, 2025·8 min read

          SSRI Exposure in the Womb May Rewire Brain Circuits

          New research suggests that prenatal exposure to SSRIs may alter brain development in ways that increase the risk of depression and anxiety later in life. Using mice and human data, scientists found that early-life SSRI exposure heightened activity in brain fear circuits, a pattern not observed in offspring of depressed mothers who did not take SSRIs.
          Read More
          This shows a brain.
          FeaturedNeurosciencePsychology
          ·April 23, 2025·6 min read

          Can Brain Scans Tell Which Antidepressant Will Work for You?

          A new study shows that brain connectivity patterns, especially in the dorsal anterior cingulate cortex, can help predict how patients with major depressive disorder (MDD) will respond to antidepressants. By combining brain imaging with clinical data, researchers developed machine learning models that accurately predicted treatment outcomes across two large trials.
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          This shows a woman and mushrooms.
          FeaturedNeurosciencePsychology
          ·April 4, 2025·3 min read

          How Psilocybin Lifts Mood Without the Hallucinogenic Trip

          Researchers have uncovered two key brain mechanisms—specific neurons and a serotonin receptor—that help explain how psilocybin produces long-lasting antidepressant effects. Their study identified pyramidal tract neurons in the medial frontal cortex and the serotonin 5-HT2A receptor as essential to the therapeutic action of psilocybin.
          Read More
          This shows a brain.
          FeaturedNeurosciencePsychology
          ·February 25, 2025·3 min read

          SSRIs May Speed Up Cognitive Decline

          A new study based on data from 18,740 dementia patients suggests that antidepressants may accelerate cognitive decline. Researchers found that patients taking antidepressants, particularly SSRIs like escitalopram, citalopram, and sertraline, experienced faster deterioration compared to those not on medication.
          Read More
          This shows a brain.
          FeaturedNeurosciencePsychology
          ·February 14, 2025·4 min read

          How Ketamine Binds to Brain Receptors to Alter Mood

          New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D. Scientists used electron cryo-microscopy to capture how ketamine binds to this receptor, revealing multiple attachment sites that influence brain activity.
          Read More
          This shows a brain.
          FeaturedNeurosciencePsychology
          ·February 14, 2025·6 min read

          Prozac Shows Promise in Fighting Infections & Sepsis

          New research suggests that fluoxetine, commonly used as an antidepressant, may also help protect against infections and sepsis. Scientists found that the drug has antimicrobial properties and helps regulate the immune response, reducing the risk of tissue and organ damage.
          Read More
          This shows the outline of a man.
          FeaturedNeurosciencePsychology
          ·December 12, 2024·8 min read

          Gut Serotonin Plays Role in Depression and Mood

          Serotonin in the gut epithelium plays a critical role in modulating mood and may provide a safer target for treating depression and anxiety. In animal studies, increasing gut serotonin improved mood symptoms without causing digestive issues, unlike systemic antidepressant treatments.
          Read More
          This shows a brain.
          Brain CancerFeaturedNeurologyNeuroscience
          ·September 22, 2024·5 min read

          Antidepressant May Help Fight Glioblastoma Brain Tumors

          Researchers have discovered that the antidepressant vortioxetine effectively combats glioblastoma, a deadly brain tumor, in lab tests and in mice. This drug, already FDA-approved, crosses the blood-brain barrier and could potentially improve treatment for glioblastoma patients when combined with standard therapy.
          Read More
          This shows a head and psychedelic swirls.
          FeaturedNeurosciencePsychology
          ·September 22, 2024·7 min read

          Psilocybin Shows Greater Long-Term Benefits Over SSRI for Depression

          A study comparing psilocybin to the SSRI escitalopram found both drugs improved depressive symptoms similarly over six months, but psilocybin offered additional psychosocial benefits. Patients taking psilocybin reported a greater sense of meaning, psychological connectedness, and improved social functioning. These results suggest psilocybin could provide a more holistic treatment option for depression, addressing both symptoms and overall well-being. While promising, psilocybin remains experimental and is only administered in controlled environments.
          Read More
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          This shows a brain model.

          3D-Printed Brain Model Mimics Neural Damage

          This shows a brain surrounded by stinky objects.

          How the Brain Decides a Smell Is Stinky

          This shows a brain.

          Low Sodium Linked to Anxiety Through Brain Chemistry Disruption

          This shows two cups of coffee.

          How You Take Your Coffee May Impact Your Risk of Early Death

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