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antidepressants

Featured Neuroscience Psychology

·June 3, 2026·8 min read

Are Long-Term Antidepressant Benefits Overstated?

A new study reveals a lack of robust evidence proving that antidepressants prevent relapse beyond 12 months.

This shows a depressed person and a pill bottle.

Featured Neuroscience Psychology

·May 20, 2026·12 min read

Arthritis Drug Rescues Hard-to-Treat Depression

The anti-inflammatory drug tocilizumab can successfully induce remission in patients struggling with treatment-resistant depression.

Featured Neuroscience Psychology

·May 19, 2026·16 min read

Buprenorphin and Ketamine Combo Provide Anti-Suicidal Effect

A sequential combination of a single ketamine infusion followed by four weeks of low-dose daily buprenorphine successfully extends the antisuicidal window of ketamine from one fleeting week to over a month.

Featured Neuroscience Psychology

·May 15, 2026·10 min read

Single Psilocybin Dose Sparks Rapid Depression Remission

Can a single dose of psilocybin replace daily antidepressants? A new randomized clinical trial shows that a 25 mg dose of the psychedelic compound delivers rapid, clinically meaningful symptom reductions for common depression in just 48 hours.

Auditory Neuroscience Featured Neuroscience Psychology

·April 20, 2026·7 min read

SSRIs May Trigger Tinnitus

A new study identifies a specific serotonin circuit that triggers the auditory system, explaining why SSRIs can worsen tinnitus and offering a new target for treatment.

This shows a scale, a pill and mushrooms.

Featured Neuroscience Psychology

·March 18, 2026·9 min read

Psychedelics Match, But Don’t Beat, Traditional Antidepressants

New research reveals that the perceived advantage of psychedelics over antidepressants disappears when the "knowledge of treatment" factor is equalized.

Featured Neuroscience Psychology

·February 13, 2026·8 min read

Antidepressants May Safeguard Against Preterm Birth Risks

Does treating depression with antidepressants during pregnancy harm the baby? A massive new study reveals that while SSRIs increase gestational diabetes risk, they also protect against preterm birth.

Featured Neuroscience Psychology

·October 30, 2025·6 min read

Common Antidepressant Eases Core Symptoms Within Two Weeks

A new analysis of the PANDA clinical trial reveals that sertraline, one of the most prescribed antidepressants, improves key emotional symptoms of depression—such as sadness, self-loathing, and suicidal thoughts—within just two weeks of treatment. Using network analysis to assess individual symptoms, researchers found that the drug also eased anxiety early on, while somatic effects like fatigue and low libido appeared but later stabilized.

Featured Neuroscience Psychology

·October 22, 2025·8 min read

Ketamine Fails to Outperform Placebo in Major Depression Trial

A large randomized and blinded clinical trial has found no additional benefit of repeated ketamine infusions over standard inpatient care for treating major depression. The study compared ketamine with a psychoactive placebo and found no meaningful differences in objective or self-reported depression scores, cognition, or quality of life.

This shows a woman, hearts, a brain, and brain waves.

Featured Neuroscience Psychology

·October 13, 2025·6 min read

EEG Test May Reveal Who Loses Libido on Antidepressants

A new study reveals that serotonin levels in the brain, measured using a simple EEG-based test, can predict who will experience sexual side effects from SSRI antidepressants. Researchers found that people with higher serotonin activity before treatment were significantly more likely to have difficulty reaching orgasm during antidepressant use.

This is a visual representation of the 5-HT1A serotonin receptor.

Featured Neuroscience Psychology

·August 2, 2025·6 min read

Fat Molecule May Control How You Feel Emotion

Scientists have uncovered how the brain’s 5-HT1A serotonin receptor—vital in mood regulation—functions at the molecular level. This receptor, a common target of antidepressants and psychedelics, prefers certain signaling pathways no matter the drug, but drugs can still vary in how strongly they activate them.

Featured Neuroscience Psychology

·July 10, 2025·7 min read

Most Antidepressant Users Don’t Face Severe Withdrawal

The largest review of antidepressant withdrawal studies shows most people don’t experience severe symptoms when stopping these medications. Analyzing data from nearly 18,000 participants, researchers found the most common withdrawal symptoms were mild, including dizziness, nausea, and nervousness.

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antidepressants

Are Long-Term Antidepressant Benefits Overstated?

Arthritis Drug Rescues Hard-to-Treat Depression

Buprenorphin and Ketamine Combo Provide Anti-Suicidal Effect

Single Psilocybin Dose Sparks Rapid Depression Remission

SSRIs May Trigger Tinnitus

Psychedelics Match, But Don’t Beat, Traditional Antidepressants

Antidepressants May Safeguard Against Preterm Birth Risks

Common Antidepressant Eases Core Symptoms Within Two Weeks

Ketamine Fails to Outperform Placebo in Major Depression Trial

EEG Test May Reveal Who Loses Libido on Antidepressants

Fat Molecule May Control How You Feel Emotion

Most Antidepressant Users Don’t Face Severe Withdrawal

Irregular Sleep Habits Linked to Increased Brain Tissue Damage

Early Life Diet Linked to Adolescent Intelligence

Does a Healthy Lifestyle Lower Dementia Risk for Those with APOE4?

Flu Drugs May Slow Cognitive Decline

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