People with OCD have six times higher Immuno-moodulin (Imood) expression that those without the disorder. Blocking Imood with the aid of an antibody reduced OCD-like behaviors in mouse models within a couple of days following treatment.
Structural mapping of both SARS and SARS-CoV-2, the virus that causes COVID-19, reveals an almost identical site on both coronaviruses to which the CR3022 antibody binds. This suggests a functionally important and vulnerable site for this family of coronaviruses.
Researchers have identified a fully human monoclonal antibody that prevents SARS-CoV-2, the virus that causes COVID-19, from infecting cultured cells. The antibody binds to a domain that is conserved in SARS-CoV-2, neutralizing the virus. The findings are an initial step towards developing a fully human antibody to prevent or treat coronavirus.
Embryonic damage caused by autoantibodies is implicated in a range of behavioral and psychological disorders, including schizophrenia, autism, and ADHD.
Johns Hopkins University researchers propose using antibodies from the plasma or serum of those who have recovered from COVID-19 to help boost the immunity of newly infected patients and for those at risk of contracting the disease. Researchers say the antibodies may bind to and neutralize SARS-CoV-2. The technique has been proven successful in prior outbreaks, including the SARS epidemic and the 1918 flu pandemic.
Researchers are sifting through millions of antibodies produced by those who have recovered from COVID-19 to find which ones neutralize the virus. The team has already identified several antibodies that block coronavirus from interacting with its receptors.
Researchers have isolated a set of antibodies from a llama which show promise for the treatment of COVID-19. The NIH-CoVnB-112 nanoantibody bound to ACE2 receptors up to ten times stronger than other lab-produced antibodies. The nanoantibody stuck directly to the ACE2 receptor binding portion of the SARS_CoV-2 spike protein. The protein could be effective in preventing coronavirus infection.
S309, a neutralizing antibody first identified in blood samples from a patient who recovered from SARS in 2003, shows promise for the treatment of COVID-19.