Epigallocatechin (EGCG), a natural antioxidant found in green tea, may help in the fight against antibiotic-resistant bacteria. EGCG restores the activity of aztreonam, an antibiotic commonly used to treat infections caused by P. aeruginosa. The bacteria is resistant to major classes of antibiotics and is currently treated with a combination of drugs.
Cannabidiol (CBD), a non-psychoactive compound extract of marijuana, has the potential to be used as an antibiotic. Researchers found CBD was remarkably effective at killing a wide range of Gram-positive bacteria, including bacteria that are resistant to common antibiotics. Additionally, CBD does not lose its effectiveness after extended treatment.
A synthetic version of a fibupeptide, which is naturally produced by the microbiome, may help in the fight against antibiotic-resistant bacteria. Lugdunin has been shown to be effective against MRSA. The findings could help in the creation of a new class of antibiotics to treat infections currently resistant to drugs on the market.
FIASMA antidepressants, such as amitriptyline and desipramine, halt the growth of four different kinds of bacterial pathogens in cell cultures and animal models. The antidepressants have shown to be effective in killing intracellular bacteria in two chlamydia infections, as well as human granulocytic anaplasmosis, a tick-borne disease that attacks white blood cells.
Gastrointestinal and immune disorders, along with sleep disruptions and seizures often co-occur at similar points of time in those diagnosed under the autism spectrum. Analyzing patterns in diagnosis of co-occurring medical conditions allowed for the identification of three subtypes of children with ASD. The findings could provide new insight into the mechanics of ASD.
Combining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.
From anti-vaccine rhetoric to the over-prescription of antibiotics, researchers suggest we should try to work together to improve public health, rather than socially shun those who ignore scientific evidence.
Study reports specific gut bacteria can influence the development of Alzheimer's disease. In mouse models, long term antibiotic treatment reduced inflammation and the formation of amyloid plaques. However, the reduction was only seen in males. Additionally, the antibiotic treatment altered the activation of microglia in the male mouse models.
Fluoroquinolone antibiotics, such as Levofloxacin and Ciprofloxacin, appear to increase the risk of peripheral neuropathy by 47%. However, there is no significant increased risk of developing neuropathy associated with amoxicillin use.
Antidepressants, such as the SSRI amitriptyline, antibiotics associated with developmental problems and sun cream components are contaminating water, and are being accumulated in fish. Exposure to the medications has effects on the molecular level to the fish. Researchers say this poses a problem as consumption of gilt-head bream is on the rise, and there could be a risk of the contaminants reaching humans via diet.
Researchers have developed a new antibiotic medication that appears to be safe and effective in treating clostridium difficile infection.