Researchers have isolated a molecule that may be under-produced in the gut of those with ALS. Using mouse models of the disease, researchers identified 11 microbial strains that became altered as the disease progressed, or before the development of symptoms.
Open sharing of scientific data and standard methods will allow researchers to collaborate on projects and accelerate understanding of neurodegenerative diseases.
Treatment with copper-ATSM helped mouse models retain behavioral performance and prevented extensive motor neuron degeneration and microglial activation associated with ALS.
While being overweight may be bad for your general health, researchers discovered an association with higher body mass index (BMI) and a reduced risk of developing ALS. Those with a BMI considered to be in the obese range had a 31% reduced risk of developing ALS, while those considered overweight had an 18% lower risk.
A minimally invasive brain implant is to be tested on humans for the first time. The device, named Stentrode, will be placed in blood vessels in the motor cortex, and researchers believe it will help improve movement and speech for those with a range of neurological disorders.
Schwann cells help protect nerves against blood clotting factors that cause degeneration, researchers report.
Researchers report exposure to common pesticides, such as PCBs, can accelerate the progression of ALS.