NU-9, a novel, non-toxic compound, targets upper motor neurons and reverses damage associated with ALS within 60 days of treatment.
Using fruit fly models of ALS, researchers discover neurons given glucose transform the power source into energy, enabling them to survive longer and function better.
Those working in production occupations, especially those exposed to volatile organic compounds, metals, combustion pollutants, and particulate matter have a higher risk of developing ALS.
Researchers report transplanting altered neural stem cells into the brains of mice genetically engineered to exhibit symptoms of ALS, delayed the progression of the disease and extended lifespan.
A new treatment for ALS, which uses a technique that turns off the mutated SOD1 gene, has passed an early phase clinical trial for safety.
Hyperactive microglia immune cells may play a significant role in the development of ALS, researchers report.
Retroviruses may be a missing causal link in diseases like ALS, multiple sclerosis and schizophrenia.
IBM Watson helps researchers identify five new genes associated with amyotrophic lateral sclerosis.
In patients with ALS, astrocytes within the brain become pro-inflammatory and tend to lose their protective function, resulting in changes in the ability to uptake glutamate.
According to researchers, astrocytes lose the ability to support motor neurons as ALS progresses.
A new study sheds light on the molecular mechanisms behind ALS.
In early stages of ALS, autophagy helps to suppress disease progression, but accelerates the spread as the disease enters into later stages, researchers report.
