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amyloid plaques

This shows glowing neurons, as though they are the target scientists discovered.

Featured Genetics Neurology Neuroscience

·February 12, 2026·8 min read

New Drug Target Could Freeze Alzheimer’s in Its Tracks

Is the IDOL enzyme the key to stopping Alzheimer's? New research shows that blocking this single target can dissolve brain plaques and boost cognitive resilience. By lowering the brain's "strongest risk factor" protein, scientists have found a new way to keep neurons communicating even under attack.

Featured Neurology Neuroscience

·January 26, 2023·5 min read

Protein Plaques Associated With Disease Are Stickier Than Thought

Study provides experimental evidence of an alternative binding site on amyloid-beta aggregates. The discovery opens the door to the development of new therapies for Alzheimer's disease.

Featured Neurology Neuroscience

·November 13, 2022·5 min read

Green Tea and Resveratrol Reduce Alzheimer’s Plaques

Two common compounds, green tea catechins and resveratrol, a compound found in red wine, reduce the formation of Alzheimer's-associated amyloid plaques in brain tissue.

Featured Neurology Neuroscience

·June 7, 2022·3 min read

Rapamycin Increases Alzheimer’s-Associated Plaques in Mice

Rapamycin, a drug approved for the treatment of cancer and transplant patients increases amyloid-beta protein plaques in the brains of mice.

This shows two hands, a brain and neurons

Featured Neurology Neuroscience

·November 29, 2021·4 min read

Potential Cause of Alzheimer’s Discovered

The form in which isomers take can increase the risk of developing dementia, researchers report. Drugs in development to improve autophagy may help prevents Alzheimer's from developing.

This is an illustration of neurons, amyloid plaques and tau

Featured Neurology Neuroscience

·October 29, 2021·4 min read

Key Alzheimer’s Feature Eliminated in Animal Model

Inhibiting the NHE6 gene abolished the formation of amyloid-beta plaques in mouse models of Alzheimer's disease.

This shows a head with a pencil erasing it

Featured Neurology

·July 28, 2020·4 min read

Alzheimer’s Protein in Blood Indicates Early Brain Changes

Blood samples taken from people enrolled in an Alzheimer's research study revealed higher levels of phosphorylated tau 217 that correlated with the presence of amyloid plaques. People with amyloid in their brains had up to three times more of the tau protein in their blood than those who had no evidence of amyloid accumulation. The higher levels of the protein were evident even in people with no signs of cognitive decline.

Featured Neurology Neuroscience Open Neuroscience Articles

·March 31, 2020·3 min read

Amyloid formation drives brain tissue loss

Animal study reveals the formation of amyloid plaques drives brain tissue loss and neurodegeneration in Alzheimer's disease. However, lithium, a drug commonly used to treat bipolar disorder, reduces the life-shortening effects of the loss.

Featured Neurology Neuroscience

·January 1, 2020·5 min read

Objective subtle cognitive difficulties predict amyloid accumulation and neurodegeneration

Amyloid accumulation occurs faster in those who have objectively-defined cognitive difficulties than older people who are considered to be cognitively normal. Mild cognitive impairment is also associated with faster hippocampal and entorhinal cortex atrophy.

Featured Neurology Neuroscience

·December 30, 2019·3 min read

What comes first, beta-amyloid plaques or thinking and memory problems?

Subtle changes in thinking and memory may appear before, or in conjunction with, the development of amyloid plaques.

Featured Neurology Neuroscience Neuroscience Videos Open Neuroscience Articles

·October 4, 2019·6 min read

Study pinpoints Alzheimer’s plaque emergence early and deep in the brain

Researchers use SWITCH technology to label amyloid plaques in mouse models of Alzheimer's disease so they could be imaged in fine detail at different ages. They were consistently able to see the plaques first emerged in deep brain structures and tracked circuits, such as the Papez memory circuit, to spread throughout the brain as the animal aged.

This shows the structure of amyloid beta

Featured Neurology Neuroscience

·May 17, 2019·3 min read

Identifying the molecular structure of one of Alzheimer’s stickier culprits

Researchers map a toxic protein associated with Alzheimer's disease. The study reports that pS8-AB40 acts as the alpha structure in polymorphism and has higher levels of cellular toxicity compared to other fibrils.

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amyloid plaques

New Drug Target Could Freeze Alzheimer’s in Its Tracks

Protein Plaques Associated With Disease Are Stickier Than Thought

Green Tea and Resveratrol Reduce Alzheimer’s Plaques

Rapamycin Increases Alzheimer’s-Associated Plaques in Mice

Potential Cause of Alzheimer’s Discovered

Key Alzheimer’s Feature Eliminated in Animal Model

Alzheimer’s Protein in Blood Indicates Early Brain Changes

Amyloid formation drives brain tissue loss

Objective subtle cognitive difficulties predict amyloid accumulation and neurodegeneration

What comes first, beta-amyloid plaques or thinking and memory problems?

Study pinpoints Alzheimer’s plaque emergence early and deep in the brain

Identifying the molecular structure of one of Alzheimer’s stickier culprits

Visual Experiences Shape the Brain’s Feedback Loop

Neural Reprogramming Restores “Young” Memory in Aging Brains

Newly Discovered Brain Pathway Triggers Weight Loss

Decoding the Cerebellum’s Secret Role in Human Language

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