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amyloid-beta

This image shows amyloid plaques associated with alzheimer disease from an HE stained brain slice.

·October 13, 2014·4 min read

Novel Culture System Replicates Course of Alzheimer’s Disease and Confirms Amyloid Hypothesis

Using an innovative culture system, researchers provide evidence supporting the amyloid hypothesis of Alzheimer's disease.

This image shows brain slice from a healthy brain and one from a brain affected by alzheimer's disease.

Featured Neurology

·September 29, 2014·3 min read

Protein that Causes Frontotemporal Dementia also Implicated in Alzheimer’s Disease

Low levels of progranulin shown to increase the formation of amyloid beta plaques and worsen memory deficits in mouse models of Alzheimer's disease.

The image shows two different brain slices. One has a buildup of amyloid beta.

Featured Genetics Neurology

·September 19, 2014·3 min read

Researchers Reveal Pathway that Contributes to Alzheimer’s Disease

Researchers report they have discovered a defect in a cell signaling pathway which contributes to the build-up of amyloid beta in those with Alzheimer's.

This image shows a shows a plastinated brain of an Alzheimer's patient.

Featured Neurology

·August 27, 2014·2 min read

Marijuana Compound May Offer Treatment for Alzheimer’s Disease

A new study reports extremely low levels of THC could slow, or even halt, the progression of Alzheimer's disease.

The image shows brain slices where compound RU 505 improved the inflammation.

Featured Neurology

·June 27, 2014·3 min read

Potential Alzheimer’s Drug Prevents Abnormal Blood Clots in the Brain

RU 505, a compound which could halt the progression of Alzheimer's may also be able to prevent abnormal blood clots in the brain, researchers report.

This image shows the location of the hippocampus in the brain.

Electrophysiology Featured Neurology

·June 18, 2014·5 min read

Blocking Brain’s ‘Internal Marijuana’ May Trigger Early Alzheimer’s Deficits

Amyloid beta has been implicated in blocking endocannabinoids in the hippocampus; impairing learning and memory long before Alzheimer's plaques form in the brain.

This image shows amyloid beta in senile plaques of the cerebral cortex.

Featured Neurology

·June 3, 2014·4 min read

New Amyloid Reducing Compound Could Be a Preventive Measure Against Alzheimer’s

In animal studies, researchers have identified a compound which reduces amyloid beta proteins by more than half.

The image shows a plastinated brain of an Alzheimer's patient from the Body World's exhibit.

Featured Neurology

·May 1, 2014·4 min read

Atypical Form of Alzheimer’s Disease May be More Widespread in Patients

Researchers have defined a sub-type of Alzheimer's disease which is relatively widespread, yet not well recognized or treated appropriately.

The image shows the different molecular structures referred to in this article. The caption best describes the image.

Featured Neurology

·April 21, 2014·4 min read

Chaperone Compounds Offer New Approach to Alzheimer’s Treatment

Researchers identify compounds that stabilize retromer protein complex and protects neurons from amyloid-beta.

The image shows brain slices from the mice.

Featured Neurology

·April 13, 2014·4 min read

New Mouse Model Could Revolutionize Research in Alzheimer’s Disease

Researchers report of creating two new mouse models of Alzheimer's disease. They believe the models could potentially revolutionize research into the neurodegenerative disease.