FeaturedNeurologyOpen Neuroscience Articles·January 26, 2016·2 min readAlzheimer-Type Brain Pathology Following Transplantation of Dura MaterResearchers have discovered Alzheimer-type pathology in the brains of some dura mater transplant recipients who later died of CJD.Read More
FeaturedNeurology·June 21, 2018·4 min readAlzheimer’s Breakthrough: Brain Metals that May Drive Disease Progression RevealedA new study provides a description of metals in the brain that may drive the progression of Alzheimer's disease.Read More
FeaturedGeneticsNeurology·December 6, 2017·5 min readAlzheimer’s Damage Reduced with Compound that Targets APOE Gene: Mouse StudyResearchers from WUSTL have identified a compound that targets APOE in mouse brains and which protects against Alzheimer's disease. The APOE4 genetic variant increases the risk of people developing Alzheimer's disease. The findings offer new possible avenues of treating the disease in humans.Read More
FeaturedNeurologyNeuroscience·April 2, 2019·9 min readAlzheimer’s diagnosis and management improved by brain scansPET imaging that helps detect dementia-related amyloid plaques significantly influences the clinical management of patients, a new study reports.Read More
FeaturedGeneticsNeurologyNeuroscience·May 1, 2019·9 min readAlzheimer’s disease is a ‘double-prion disorder’Self-propagating amyloid and tau act as prions in the pathology of Alzheimer's disease. Higher levels of the prions in human brain samples were strongly correlated with early onset of Alzheimer's and death at a younger age.Read More
FeaturedNeurologyOpen Neuroscience Articles·March 22, 2017·5 min readAlzheimer’s Disease Linked to the Metabolism of Unsaturated FatsA new study report omega 3 and omega 6 unsaturated fatty acids are significantly decreased in the brains of people with Alzheimer's.Read More
FeaturedNeurology·October 31, 2017·4 min readAlzheimer’s Disease Might Be a ‘Whole Body’ ProblemUsing a technique called parabiosis on pairs of mice, researchers discover what they call 'cancer like mobility' of amyloid beta, reporting it can travel to the brain from other parts of the body.Read More
FeaturedNeurologyOpen Neuroscience Articles·September 29, 2015·5 min readAlzheimer’s Disease Progression Influenced by Disruption of Blood-Brain BarrierA new study reports amyloid beta induces a strong inflammatory response, destroying the blood-CSF barrier.Read More
FeaturedNeurologyNeuroscienceVisual Neuroscience·March 10, 2021·5 min readAlzheimer’s Disease Protein Linked to Common Sight LossExposing retinal pigment epithelium cells in mouse models to amyloid-beta resulted in retinal pathologies similar to those seen in human age-related macular degeneration.Read More
FeaturedNeurology·December 6, 2013·3 min readAlzheimer’s Drug Discovery: Looking Under the Right ROCKResearchers have discovered a potential drug which can force BACE into different parts of a cell, reducing its ability to produce amyloid beta.Read More
FeaturedNeurology·January 25, 2018·4 min readAlzheimer’s Drug Falls Short in Large Clinical TrialResearchers report a drug developed to target amyloid plaques in those with Alzheimer's does not significantly slow cognitive decline.Read More
FeaturedNeurology·August 1, 2018·4 min readAlzheimer’s Drug May Stop Disease If Used Before Symptoms AppearResearchers report memantine, an FDA approved drug, may not only alleviate symptoms of mild Alzheimer's disease, but could also prevent progression of the disease if used before symptoms appear.Read More