Researchers were able to dampen hyperexcitability associated with seizure disorders in rodent models by inducing biochemical alterations with glucosamine, a dietary supplement.
Using cryo-electron microscopy, researchers have been able to capture how glutamate opens glutamate receptor ion channels. The Nature study provides significant insight into how receptors can mediate brain function.
Researchers used a new technique to discover what happens when Parkinson's patients receive cell transplants.
Using optogenetics to manipulate the brains of opioid addicted mice, researchers discover a neural pathway that appears to be responsible for symptoms of withdrawal.
According to a new mathematical model of seizures, only the conductivity of the AMPA receptors in neurons in the temporal lobe significantly change, leading to stronger excitation and synaptic signals.
Oxytocin, the so-called "love hormone," could help to treat cognitive disorders, including Alzheimer's disease. Researchers demonstrated oxytocin reversed the effects of amyloid-beta on hippocampal LTP in mice. The findings suggest oxytocin could be used as a therapeutic for the treatment of Alzheimer's disease and other dementias.
A new study reports mice that express a reduced amount of the TMEM108 protein were more likely to express schizophrenia like symptoms, including memory and navigational problems.
A new study reports a protein made by astrocytes plays a critical role in brain plasticity by assisting with neural maturation and flexibility.
Findings could help researchers develop new treatments for the most devastating forms of multiple sclerosis and other demyelinated diseases.