Receptor potentiation was observed when the antagonists bind to receptors that consist of different subunits, where it acts as a subunit.
A newly designed synthetic compound could act as a prototype for a novel class of drugs to treat neurological damage.
Oxytocin, the so-called "love hormone," could help to treat cognitive disorders, including Alzheimer's disease. Researchers demonstrated oxytocin reversed the effects of amyloid-beta on hippocampal LTP in mice. The findings suggest oxytocin could be used as a therapeutic for the treatment of Alzheimer's disease and other dementias.
Learning and memory abilities may vary, depending on the nature of individual experiences early in life.
According to a new mathematical model of seizures, only the conductivity of the AMPA receptors in neurons in the temporal lobe significantly change, leading to stronger excitation and synaptic signals.
A new study reports brown fat interacts with secretin, a gut hormone, to signal the feeling of fullness to the brain while eating.