Researchers say the combination of low muscle mass and strength in the context of high fat mass, could be a predictor of cognitive function in older adults. Sarcopenic obesity could be used to predict risk factors for developing dementia, the study reports.
Using a line of genetically modified mice, researchers discover boosting acetylcholine can disturb cognitive function.
Researchers have identified nine risk factors during different stages in life that may increase a person's likelihood of developing dementia. At least 35% of dementia cases, researchers say, may be directly linked to these risk factors. By taking steps to reduce risks and by improving education, it is estimated that the incidence of dementia can be reduced by as much as 20%.
15 protein biomarkers have been identified as being linked to late-onset dementias. The biomarkers can predict cognitive decline and risk for dementia up to 20 years before the onset of symptoms.
A 3D human tissue culture model demonstrated a possible causal relationship between Alzheimer's disease and herpes simplex virus 1 (HSV-1) infection. 40 Alzheimer's associated genes were over-expressed in the HSV-1 infected brain tissue, including genes associated with the production of amyloid-beta.
Study reports modifying twelve risk factors over your lifetime could reduce dementia risk by 40%.
MW-151, a new drug that blocks 'bad' inflammation in the brain is about to be tested in a new human trial. Researchers believe the new drug could help stave off dementia.
Reducing the expression of the protein TOM1 in mouse models of Alzheimer's disease increased the pathology, exacerbated cognitive problems, and raised levels of inflammation in the brain. Restoring TOM1 reversed the effects. Findings suggest a new therapeutic target for treating dementia.