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Alzheimer’s disease

·September 29, 2025·6 min read

Alzheimer’s Study Finds Blood-Brain Barrier Largely Intact

A new study suggests that the blood-brain barrier (BBB) remains intact in a widely used mouse model of Alzheimer’s disease. Using a tracer molecule and advanced analysis, scientists found no significant leakage across brain regions, even near amyloid plaques.

Featured Genetics Neurology Neuroscience

·September 19, 2025·4 min read

Unlocking Brain Cell Crosstalk Reveals New Path in Alzheimer’s

A new study reveals that Alzheimer’s disease involves more than just plaques and tangles; it also stems from disrupted communication between brain cells. Using advanced imaging and computational modeling, scientists mapped how neurons and glial cells interact at the molecular level.

This shows a brain, immune cells, and a scale.

Featured Neurology Neuroscience

·September 18, 2025·5 min read

Alzheimer’s Research Shifts Toward Immune System Balance

Alzheimer’s disease affects over 55 million people worldwide and has long been linked to toxic protein buildup and chronic inflammation in the brain. A new review shows that adaptive immune cells—T and B cells—also play a crucial role, sometimes worsening brain damage, sometimes offering protection.

This shows older people walking in a park and a brain.

Featured Neurology Neuroscience

·September 16, 2025·7 min read

Lifestyle Changes Show Power to Prevent Alzheimer’s

A growing body of research underscores that Alzheimer’s and cognitive decline are not inevitable parts of aging. Lifestyle interventions targeting exercise, diet, social engagement, and cognitive stimulation have been shown in large clinical trials to improve brain function and slow decline.

Featured Genetics Neurology Neuroscience

·September 11, 2025·5 min read

Defective Exosome Production Linked to Alzheimer’s Gene Mutation

New research reveals that a gene mutation tied to Alzheimer’s disease disrupts the production of exosomes, tiny cellular particles essential for communication between brain cells. Cells with a defective SORLA protein produced about 30% fewer exosomes, and those exosomes were up to 50% less effective at supporting cell growth.

Featured Neurology Neuroscience

·September 10, 2025·5 min read

Cooler Nights and Brighter Days Boost Sleep in Dementia Patients

A large-scale study shows that indoor environmental changes—such as cooler bedroom temperatures at night and brighter indoor light during the day—can significantly improve sleep in people living with dementia. Researchers analyzed over 26,000 days of data using contactless sensors placed in participants’ homes.

Featured Neurology Neuroscience

·September 2, 2025·5 min read

3-Minute Brainwave Test Detects Alzheimer’s Years Before Symptoms

A team of researchers has developed a simple three-minute brainwave test called Fastball EEG that can detect early signs of memory impairment linked to Alzheimer’s disease. Unlike traditional memory tests, it is passive and requires no active participation, making it more objective and accessible.

Featured Genetics Neurology Neuroscience

·September 2, 2025·9 min read

Alzheimer’s Linked to Epigenomic Breakdown, Not Just Plaques

A new large-scale study shows that Alzheimer’s disease is marked by the erosion of epigenomic control, where brain cells lose the ability to maintain stable gene expression. Using a multi-region atlas of 3.5 million cells, researchers found that vulnerable cells in key memory regions such as the hippocampus suffer breakdowns in nuclear compartmentalization and lose their “epigenomic information.”

Featured Neurology Neuroscience

·August 29, 2025·5 min read

Gut Immune Cells Found Migrating to Alzheimer’s Brain

Researchers have uncovered a surprising link between gut immune cells and the brain in Alzheimer’s disease. In mice, antibody-producing B cells that normally reside in the gut were found migrating into brain border regions, influenced by chemokine signals from inflammatory brain cells.

Featured Neurology Neuroscience Visual Neuroscience

·August 28, 2025·6 min read

Brain Rewiring Patterns May Predict Alzheimer’s Years in Advance

Researchers have discovered that people with Alzheimer’s show unusually high neural flexibility—the constant reorganizing of brain networks—even while resting. In a large study of older adults, higher neural flexibility in the visual network predicted which healthy participants would later develop dementia.

This shows a brain surrounded by proteins in a snow globe.

Featured Genetics Neurology Neuroscience

·August 26, 2025·6 min read

Blocking a Brain “Death Complex” Slows Alzheimer’s

Scientists have discovered that a toxic complex formed between NMDA receptors and TRPM4 channels drives neuron death in Alzheimer’s disease. Using a novel molecule called FP802, researchers were able to break apart this “death complex” in mice, preventing cognitive decline, synapse loss, and mitochondrial damage.

Featured Neurology Neuroscience Visual Neuroscience

·August 26, 2025·6 min read

Eye Exams Could Spot Alzheimer’s Decades Before Symptoms Appear

Eye exams could help detect Alzheimer’s disease years before symptoms arise. By studying mice with a common genetic mutation, researchers found abnormal changes in retinal blood vessels that paralleled brain changes linked to dementia risk.