A new study reports cumulative pesticide exposure is linked to an increased risk for developing ALS.
Riluzole, a drug commonly prescribed to slow the progression of ALS, appears to slow brain metabolic decline and improve cognitive performance in those with mild Alzheimer's disease.
Researchers have identified a modifier gene that affects the risk of developing degenerative myelopathy, a canine disease similar to ALS in Welsh corgis.
By increasing the signaling activity of a protein called muscle skeletal receptor tyrosine-protein kinase (MuSK), researchers were able to keep nerve cells attached to muscle longer into the progression of the disease in a mouse model of ALS.
Researchers have developed a brain machine interface which can control a lower limb exoskeleton.
Neurturin, a muscle-produced protein, improves muscular metabolism, motor coordination, and exercise performance in mouse models. The discovery could have implications for treating ALS and other disorders associated with neurological disorders that affect muscles.
Axon pruning becomes reactivated in neurodegenerative diseases, a new study finds.
According to new research, the C9orf72 mutation causes long strands of RNA to block specific pathways which usually move proteins into a cell's nucleus.
Performing post-mortem staging of the brains and spinal cord tissue of patients with ALS, researchers discover the neurodegenerative disease could progress from one start point in the CNS to other regions of the brain and spinal cord.