Using neurons created from iPS cells derived from people with ALS, researchers develop a new drug which appears to halt the impact of the genetic mutations in some forms of ALS and dementia.
Researchers discover how a genetic code variation in the C9orf72 gene alters the shape of DNA, making cells more vulnerable to stress and apoptosis.
Researchers have developed a technique to make brain controlled prosthetics more precise. A pilot clinical trial of the neuroprosthesis is underway for people with paralysis and ALS.
Researchers found an increased inflammatory signal in patients with the C90rf72 subtype of ALS. The increased inflammatory biomarkers could be found in peripheral serum tests.
Microglia plays crucial roles both in healthy and diseased brains, a new study reports.
Mislocalization of the TDP-43 protein alters the genetic instructions for UNC13A. The findings provide a potential new therapeutic target for the treatment of ALS and frontotemporal dementia.
According to a new study, researchers have devised a new way to detect chemical damage to DNA that leads to genetic mutations which are responsible for an array of diseases, including ALS and other neurodegenerative diseases.
A new study reports on the role the protein TDP-43 plays in the development of Alzheimer's disease.