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alpha-synuclein

Featured Neurology Open Neuroscience Articles

·December 10, 2018·4 min read

Two Compounds in Coffee May Team Up to Fight Parkinson’s

A new study reports caffeine plus another compound found in the waxy coating of coffee beans may help protect the brain against Parkinson's disease.

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Featured Neurology Open Neuroscience Articles

·October 13, 2013·3 min read

Two Forms of Parkinson’s Disease Identified

Researchers have succeeded in characterizing and producing two different types of alpha-synuclein aggregates. One of which is more toxic and has greater capacity to invade neurons.

Featured Neurology Neuroscience

·June 10, 2021·6 min read

Understanding Gut Inflammation May Hold Clues to Mitigating Parkinson’s Onset

Chronic gut inflammation can trigger the clumping of alpha-synuclein in the walls of the colon, a new study reports. Researchers found chronic inflammation in the gut during early life can exacerbate the clumping of alpha-synuclein in the brains of older mice. The findings add to a growing body of evidence which links gut health to Parkinson's disease.

Featured Genetics Neurology Open Neuroscience Articles

·August 23, 2020·4 min read

Unique Protein Structures Could Hold the Key to Parkinson’s Disease

Researchers have discovered a series of misfolded alpha-synuclein protein structures never previously observed. The alpha-synuclein fibers were larger than previously reported and adopted a striking variety of shapes. The work lays the foundation for a detailed analysis of misfolded alpha-synuclein structures and could provide a better understanding of the neurobiology of Parkinson's disease.

Neuroscience

·June 20, 2011·2 min read

USC Researchers Find New Clues About Protein Linked To Parkinson’s Disease

Structural biologists at the Keck School of Medicine of USC are the first to measure the energy difference between protein...

Featured Neurology Neuroscience

·February 16, 2023·4 min read

Using Stool Samples as an Indicator of Early Form of Parkinson’s

Researchers report a greater concentration of alpha-synuclein aggregates was found in stool samples from Parkinson's patients who suffered isolated REM-sleep behavior disorder.

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Featured Neurology

·July 9, 2017·5 min read

What’s the Difference Between Alzheimer’s Disease and Dementia?

A common misconception is that Alzheimer's disease and dementia are the same thing. Alzheimer's disease is simply one form of dementia. Researchers from Texas A&M describe how Alzheimer's and other forms of dementia impact the lives of both patients and their families, and provide new insights into minimizing the risks of developing neurodegenerative conditions.

This shows the outline of two bodies. One has the head highlighted red, the other has the gut highlighted red

Featured Neurology Neuroscience Open Neuroscience Articles

·November 7, 2019·4 min read

Where does Parkinson’s disease start? In the brain or gut? Or both?

Lewy body disorders, including Parkinson's disease and Lewy body dementia, comprise of two distinct subtypes. One subtype originates in the peripheral nervous system (PNS) of the gut and spreads to the brain. The other originates in the brain, or enters the brain via the olfactory system, before spreading to the brainstem and PNS.