Natural killer cells may play a critical role in regulating and restraining neuroinflammation and protein clumping associated with Parkinson's disease.
The Parkinson's-associated protein alpha-synuclein appears to act as a "toggle switch" that helps control vesicle transportation and gene expression. In a diseased state, this delicate balance is broken. The findings have implications for the development of new treatments for Parkinson's disease.
A protein associated with Parkinson's disease regulates neurotransmission by self association, a new study reports.
Researchers improve both animal and cell models for Parkinson's disease, a new study reports.
A new study reports the interaction between a mitochondrial protein called TOM20 and alpha-synuclein leads to neurodegeneration in Parkinson's disease.
Researchers have identified proteins in the blood that could reflect nerve cell damage.
A Nature Neuroscience study reveals the normal role of alpha-synuclein, a protein implicated in Parkinson's disease. Researchers say understanding how the protein normally acts may give insights into how it might fail.
Researchers have developed a new method which nitrates alpha-synuclein to simulate the nitration patterns seen in PD.
A new study sheds light on how ziram causes the loss of the main source of dopamine in the central nervous system.
Biopsy of submandibular gland may reveal signature alpha-synuclein associated with Parkinson's disease and dementia with Lewy bodies.
A new study reports the combination of a toxic herbicide and lectins may trigger Parkinsonism after the toxins travel from the stomach to the brain.
A new study links a lack of SMG1 to protein aggregates associated with Parkinson's disease and other neurodegenerative diseases.