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alpha-synuclein

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Featured Neurology Neuroscience

·March 13, 2020·5 min read

‘Natural killer’ cells could halt Parkinson’s progression

Natural killer cells may play a critical role in regulating and restraining neuroinflammation and protein clumping associated with Parkinson's disease.

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Featured Genetics Neurology Neuroscience

·June 9, 2022·5 min read

A ‘Double Life’ for a Key Parkinson’s Disease Protein

The Parkinson's-associated protein alpha-synuclein appears to act as a "toggle switch" that helps control vesicle transportation and gene expression. In a diseased state, this delicate balance is broken. The findings have implications for the development of new treatments for Parkinson's disease.

This image shows positive α-Synuclein staining of a Lewy body in a patient with Parkinson's disease.

Featured Neurology

·September 29, 2014·2 min read

A “Frenemy” in Parkinson’s Disease Takes to Crowdsourcing

A protein associated with Parkinson's disease regulates neurotransmission by self association, a new study reports.

Image shows Lewy bodies.

Featured Neurology

·February 1, 2016·3 min read

A Better Model for Parkinson’s Disease

Researchers improve both animal and cell models for Parkinson's disease, a new study reports.

Image shows positive α-Synuclein staining of a Lewy body from a patient who had Parkinson's disease.

Featured Genetics Neurology

·June 8, 2016·5 min read

A Key to Parkinson’s Neurodegeneration Identified

A new study reports the interaction between a mitochondrial protein called TOM20 and alpha-synuclein leads to neurodegeneration in Parkinson's disease.

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Featured Neurology

·June 9, 2016·4 min read

A New Biomarker for Nerve Cell Damage

Researchers have identified proteins in the blood that could reflect nerve cell damage.

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Featured Neurology

·July 28, 2017·4 min read

A New Insight into Parkinson’s Disease Protein

A Nature Neuroscience study reveals the normal role of alpha-synuclein, a protein implicated in Parkinson's disease. Researchers say understanding how the protein normally acts may give insights into how it might fail.

This shows immunohistochemistry for alpha-synuclein showing positive staining (brown) of an intraneural Lewy-body in the Substantia nigra in Parkinson's disease.

Featured Neurology

·April 2, 2015·3 min read

A New Tool for Understanding Parkinson’s Disease

Researchers have developed a new method which nitrates alpha-synuclein to simulate the nitration patterns seen in PD.

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Featured Neurology Open Neuroscience Articles

·June 15, 2016·4 min read

A Protective Strategy Against Pesticide Linked Parkinson’s Disease

A new study sheds light on how ziram causes the loss of the main source of dopamine in the central nervous system.

Image shows nerve fiber in the submandibular gland.

Featured Neurology

·April 12, 2016·4 min read

A Tissue Biomarker for Dementia With Lewy Bodies and Parkinson’s Disease

Biopsy of submandibular gland may reveal signature alpha-synuclein associated with Parkinson's disease and dementia with Lewy bodies.

stomach

Featured Neurology Neuroscience Open Neuroscience Articles

·December 4, 2018·5 min read

A Toxin That Travels From Stomach to Brain May Trigger Parkinson’s

A new study reports the combination of a toxic herbicide and lectins may trigger Parkinsonism after the toxins travel from the stomach to the brain.

The slides shown are taken from the research, The caption best explains the image.

Featured Neurology Open Neuroscience Articles

·October 30, 2013·2 min read

Absence of the SMG1 Protein Could Contribute to Parkinson’s and Other Neurological Disorders

A new study links a lack of SMG1 to protein aggregates associated with Parkinson's disease and other neurodegenerative diseases.

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