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          ALLO

          This shows a pregnant woman
          AutismFeaturedNeurosciencePsychology
          ·August 16, 2021·7 min read

          Loss of Placental Hormone Linked to Brain and Social Behavior Changes

          Reduced amounts of the placental hormone allopregnanolone caused behavioral and developmental changes in the brains of male mouse offspring similar to those seen in autism.
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          This shows myelin in a brain slice
          AutismFeaturedNeuroscience
          ·October 21, 2019·2 min read

          Autism spectrum disorder risk linked to insufficient placental steroid

          When the hormone allopregnanolone (ALLO) abruptly decreases or stops during pregnancy, children are more likely to develop autism. Researchers report a single ALLO injection during pregnancy can avert the brain abnormalities and social behaviors associated with ASD in experimental mouse models of autism.
          Read More
          This shows the lead research looking after a baby in a neonatal ward
          AutismFeaturedNeuroscience
          ·April 27, 2019·3 min read

          Placental function linked to brain injuries associated with autism

          Disruptions in the supply of allopregnanolone, a hormone created by the placenta late in pregnancy, to the developing fetus can leave children more vulnerable to brain injuries associated with ASD. Losing the supply of ALLO alters cerebellar development, an area of the brain critical for motor coordination and social cognition, impacting the post-birth development of cerebellar white matter. An experimental model revealed deficient cerebellar white matter resulted in social impairments and an increase in repetitive behaviors, two hallmark features associated with autism.
          Read More
          Image of a scale and tape measure.
          FeaturedNeurosciencePsychology
          ·November 10, 2017·6 min read

          Both Obese and Anorexic Women Have Low Levels of ‘Feel Good’ Neurosteroid

          Women who suffer from eating disorders from anorexia to obesity have lower levels of allopregnanolone, a progesterone metabolite previously linked to mood disorders, a new study reports.
          Read More

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          This shows a marmoset.

          GPS of the Brain: Marmoset Gaze Reveals New Insights into Spatial Navigation

          This shows a neuron.

          BigNeuron: Revolutionizing Neuron Reconstruction with AI

          This shows a person's head.

          Vitamin D’s Crucial Role in Dopamine Function and Schizophrenia

          This shows a colorful outline of a dog's head.

          Canine Brain Atlas Sheds Light on Evolution of Human Brain Function

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