Study reveals a previously unrecognized family connection to alcohol use disorder, the drinking habits of a person's in-laws. People married to those who experienced parental alcohol misuse as a child are more likely to develop an addiction to alcohol, even if the spouse has no history of a personal battle with alcohol use.
Researchers hypothesize vitamin B1 (thiamine) deficiency may play a significant role in dementia associated with alcohol use disorder. It is known iron deposits in the brain contribute to neurodegenerative diseases. Those with AUD have elevated levels of both iron in their blood and thiamine deficiency. Thiamine is vital for maintaining the blood-brain barrier. Thiamine deficiency associated with AUD disrupts the integrity of the BBB, allowing for more iron deposits within the brain and leading to oxidative tissue damage.
Study reveals binge drinking is associated with more widespread neural dysfunction than previously believed. In those who binge drink, the visual areas of the brain show unusually high levels of activation. Additionally, those who binge drink have more difficulty in feeling empathy for others.
Low-level exposure to lead during development does not lead to alcohol use disorder, but does alter the neural circuits in a way that if addiction occurs, it makes it harder to refrain from returning to addiction related behaviors.
Manipulating memory via optogenetics mitigated addiction-related behaviors.
People who are most sensitive to the pleasurable and rewarding effects of alcohol are at greater risk of developing alcohol use disorders.
A new series of studies review the roles neuroplasticity and neurogenesis play in alcohol addiction and recovery.
A new study reveals sex differences in the way those with alcohol use disorder process facial emotions. Men with AUD showed greater activation in frontal brain areas when processing facial emotions. The increased activation was not seen in women with AUD.