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alcohol use disorder

·March 30, 2026·6 min read

Metabolites “Rewrite” Brain Genes in Addiction

Researchers found that alcohol metabolites directly regulate gene expression in the brain. The ventral hippocampus is especially sensitive to these epigenetic changes, providing a new molecular target for treating alcohol use disorder.

This shows a crowd of people and one person with a thought bubble and a bottle inside it.

Featured Neuroscience Psychology

·March 2, 2026·6 min read

Why Socializing Loses to Alcohol in Addiction

New research reveals that activity in the anterior insula primes the brain to choose alcohol over social interaction, offering a new target for addiction treatment.

This shows a brain in a wine glass with a syringe above it. Behind is a strand of DNA.

Featured Neuroscience

·February 21, 2026·7 min read

Mounjaro’s Active Ingredient Slashes Alcohol Intake

From weight loss to sobriety. New research reveals how the active ingredient in Mounjaro "mutes" the brain's reward system to slash alcohol cravings.

This shows a person holding a joint and a glass of scotch.

Featured Neuroscience Psychology

·November 19, 2025·7 min read

Cannabis Blunts Alcohol Cravings

A randomized, placebo-controlled trial shows that cannabis with active THC reduces immediate alcohol cravings and lowers drinking levels in heavy-drinking young adults. After smoking THC, participants not only drank less, they waited longer before taking the first sip and reported lower urges to drink.

Featured Neuroscience

·September 30, 2025·6 min read

Targeting the Cerebellum Could Ease Alcohol Withdrawal Symptoms

Researchers have identified the cerebellum as a promising target for easing alcohol withdrawal, the stage of alcohol use disorder that drives many people back to drinking. In mice, withdrawal symptoms were alleviated by calming overactive cerebellar neurons, either through genetic tools or a synthetic compound.

Featured Neuroscience

·June 3, 2025·7 min read

Ibudilast Fails to Beat Placebo in Alcoholism Trial, Except in Women

A recent clinical trial found that ibudilast, a drug once promising for alcohol use disorder, was no more effective than a placebo overall. While all participants reduced their drinking, women on ibudilast showed a greater drop in drinks per day, hinting at a gender-specific benefit.

This shows outlines of people and glasses.

Featured Neuroscience Psychology

·May 7, 2025·4 min read

Social Drinking, Not Solitary, Drives Most Alcohol-Related Harm

New research challenges the stereotype of the solitary drinker, showing that social drinking plays a central role in the development and consequences of alcohol use disorder. Studies reveal people consistently drink more in social settings, where heavy drinking often leads to serious harms like violence, risky sex, and traffic fatalities.

Featured Neuroscience Psychology

·May 4, 2025·12 min read

Why Alcohol Hits Women Harder

Alcohol use among women has surged to match men’s rates, but women face far greater health risks even at lower consumption levels. A growing body of research is uncovering key neurobiological sex differences that influence why and how women drink, with stress being a more prominent motivator for women.

Featured Neuroscience

·December 20, 2024·4 min read

How Alcohol Impairs the Brain’s Ability to Adapt and Learn

Alcohol use disorder (AUD) disrupts cognitive flexibility, crucial for learning and adapting to change. New research reveals that chronic alcohol exposure alters the firing patterns of cholinergic interneurons (CINs), key neurons in the brain’s striatum that regulate dopamine and influence reward-driven learning.

Featured Neuroscience

·November 27, 2024·4 min read

Does Alcohol Consumption Contribute to Hair Loss?

A systematic review and meta-analysis explored whether alcohol consumption influences androgenetic alopecia (AGA), the most common form of hair loss. The study found a modest association between drinking and AGA, with drinkers 1.4 times more likely to experience AGA than non-drinkers, though the link was not statistically significant.

Featured Neuroscience Psychology

·November 27, 2024·4 min read

Finger Lengths May Reveal Insights Into Drinking Habits

The relative lengths of your fingers might be linked to your alcohol consumption patterns. Researchers found that individuals with longer 4th (ring) fingers relative to 2nd (index) fingers, indicating high prenatal testosterone exposure, are more likely to consume alcohol.

Featured Neuroscience Psychology

·November 12, 2024·5 min read

After the Pandemic, Alcohol Use Remains Elevated

U.S. alcohol use increased during the COVID-19 pandemic and has stayed elevated post-pandemic, posing serious health risks. Heavy drinking rose by 20% during the pandemic, and the increase continued in 2022. This trend spanned across most demographics, with the highest rise among adults aged 40-49.