Older mice given anti-inflammatory medication were better able to learn new tasks and became almost as adept at learning as mice half their age.
A synthesized small-molecule drug blocks the TGF-beta receptor in astrocytes and traverses the blood-brain barrier in mice. When administered, the drug lowered receptor activity to that seen in younger mice and reduced inflammation. The aged mice were able to navigate mazes and learn spatial tasks as well as younger mice.
Interferon betas, a class of drugs commonly prescribed to those with multiple sclerosis reduces the binding of zinc, C-peptide and albumin to red blood cells.
