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Featured Neuroscience Open Neuroscience Articles

·May 20, 2020·3 min read

COVID-19 cytokine storm: Possible mechanism for the deadly respiratory syndrome

SARS-CoV-2, the virus responsible for COVID-19, enters human cells by attaching to ACE2 and utilizing TMPRSS2. Drugs that block ACE2 or inhibit the enzyme could help treat the coronavirus, but only during early infection. As the infection progresses, SARS-CoV-2 becomes engulfed in human cells, reducing the number of ACE2 receptors on a cell and leading to an increase of angiotensin II in the blood. Angiotensin II triggers an inflammatory pathway, providing a positive feedback cycle, named IL-6 amplifier, resulting in excessive immune activation and the cytokine storm associated with severe COVID-19.

Featured Neuroscience Open Neuroscience Articles

·March 23, 2020·2 min read

ACE inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19

Researchers confirm ACE inhibitors and ARBS medications may increase the risk of patients with COVID-19 developing more severe symptoms.

Featured Neuroscience

·April 23, 2020·5 min read

Key nose cells identified as likely COVID-19 virus entry points

The receptor protein ACE2 and the TMPRSS2 protease that can activate SARS-CoV-2 entry are expressed in cells on the inner lining of the nose. Mucus producing goblet cells and ciliated cells in the nose have the highest levels of both proteins, making them the most likely initial infection route for coronavirus. Additional key entry points were found in the cells of the eye's cornea and the intestines. This suggests other points of infection could be via the tear ducts and through fecal-oral transmission.

Featured Genetics Neurology Neuroscience

·May 26, 2020·2 min read

Researchers flag similarities between COVID-19 deaths and severe rheumatic illnesses

After natural killer immune cells kill virus-infected cells, T and B immune cells produce cytokines. This makes the immune reaction stronger and results in the cytokine storm associated with severe COVID-19 infection.

Featured Neuroscience Neuroscience Videos

·April 5, 2020·5 min read

What the coronavirus does to your body that makes it so deadly

Researchers explore why COVID-19 is more deadly compared to the flu and other viruses.

Featured Neuroscience Open Neuroscience Articles

·April 23, 2020·4 min read

Evidence suggests COVID-19 isn’t sexually transmitted

Previous studies report COVID-19 may be present in the testes. Researchers report coronavirus is unlikely to spread via semen, and the chances of the infection being spread through sexual transmission are remote.

Featured Neurology Neuroscience Psychology

·May 15, 2020·6 min read

The Potential of COVID-19 to Infect the Brain

From losing the sense of taste or smell to developing an increased risk of stroke, researchers investigate both the known and potential long-term implications of COVID-19 infection in the brain.

Featured Genetics Neuroscience Open Neuroscience Articles

·May 11, 2020·6 min read

Men’s blood contains greater concentrations of enzyme that helps COVID-19 infect cells

Men have higher concentrations of ACE2 in their blood than women. As ACE2 enables coronavirus to infect cells, the findings may explain why men are more susceptible to COVID-19 infection than women.

Featured Neuroscience

·May 12, 2020·2 min read

Exploring why some COVID-19 patients lose their sense of smell

ACE2 and TMPRSS2, two proteins required for SARS-CoV-2 entry, are produced in cells in the nasal cavity that contribute to odor detection. The findings may explain why people with coronavirus often describe the loss of the sense of smell as a symptom of the virus.

This shows dying neurons and areas of brain tissue infected with SARS_CoV_2

Featured Neurology Neuroscience

·January 12, 2021·3 min read

SARS_CoV_2 Can Infect Neurons and Damage Brain Tissue

SARS_CoV_2, the virus responsible for COVID-19, can directly enter the nervous system. The virus can infect the brain, causing alterations in blood vessels and directly disrupt oxygen supply to the organ.

Featured Neuroscience Open Neuroscience Articles

·April 29, 2020·4 min read

COVID-19 study shows that men have over double the death rate of women

Males who contract COVID-19 have 2.5 times the death rate of women. Being males is a significant risk factor for worse disease severity, regardless of age. Researchers found a similar trend in data from the 2003 SARS outbreak. The study speculates the reason why males are more prone to negative outcomes of coronavirus is due to levels of ACE2, which is significantly higher in males than females.

Featured Neurology Neuroscience Open Neuroscience Articles

·October 19, 2021·4 min read

Viral Infections Could Promote Neurodegeneration

Some viral infections could increase intercellular spreading of protein aggregates associated with neurodegenerative disorders, increasing the risk for developing Alzheimer's, Parkinson's, and other neurodegenerative diseases.

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ACE2

COVID-19 cytokine storm: Possible mechanism for the deadly respiratory syndrome

ACE inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19

Key nose cells identified as likely COVID-19 virus entry points

Researchers flag similarities between COVID-19 deaths and severe rheumatic illnesses

What the coronavirus does to your body that makes it so deadly

Evidence suggests COVID-19 isn’t sexually transmitted

The Potential of COVID-19 to Infect the Brain

Men’s blood contains greater concentrations of enzyme that helps COVID-19 infect cells

Exploring why some COVID-19 patients lose their sense of smell

SARS_CoV_2 Can Infect Neurons and Damage Brain Tissue

COVID-19 study shows that men have over double the death rate of women

Viral Infections Could Promote Neurodegeneration

Wasabi Compound Enhances Memory

Genes Associated with Earlier and Higher Reproduction Linked to Accelerated Aging

Novel Multiple Sclerosis Treatment Shows Promise

Brain’s Response to Crucial Language Hub Removal: New Insights

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