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Featured Neuroscience Open Neuroscience Articles

·March 23, 2020·2 min read

ACE inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19

Researchers confirm ACE inhibitors and ARBS medications may increase the risk of patients with COVID-19 developing more severe symptoms.

Featured Neuroscience

·May 12, 2020·2 min read

Exploring why some COVID-19 patients lose their sense of smell

ACE2 and TMPRSS2, two proteins required for SARS-CoV-2 entry, are produced in cells in the nasal cavity that contribute to odor detection. The findings may explain why people with coronavirus often describe the loss of the sense of smell as a symptom of the virus.

Featured Genetics Neuroscience

·May 18, 2020·3 min read

Smokers more likely to express ACE2 protein that coronavirus uses to enter human cells

Smoking increases the gene expression of ACE2, a protein that binds to SARS-CoV-2, increasing the risk of coronavirus infection. Findings suggest long-term smokers could have an increase of ACE2 in the lungs, leading to higher rates of morbidity in COVID-19 patients.

Featured Neurology Neuroscience

·January 5, 2021·5 min read

How COVID-19 Is Likely to Impact the Brain

Using over a century of data from other pandemics, and applying knowledge about the current COVID-19 infection, researchers predict the long term effects coronavirus will have on the brain and nervous system.

Featured Neuroscience Open Neuroscience Articles

·April 29, 2020·4 min read

COVID-19 study shows that men have over double the death rate of women

Males who contract COVID-19 have 2.5 times the death rate of women. Being males is a significant risk factor for worse disease severity, regardless of age. Researchers found a similar trend in data from the 2003 SARS outbreak. The study speculates the reason why males are more prone to negative outcomes of coronavirus is due to levels of ACE2, which is significantly higher in males than females.

Featured Genetics Neuroscience

·April 7, 2020·5 min read

Coronavirus receptor abundantly expressed in certain progenitor cells

Certain progenitor cells in the bronchi are mainly responsible for producing coronavirus receptors. These cells normally develop into respiratory tract sells linked with cilia, that clear bacteria out of the lungs.

Featured Neuroscience Open Neuroscience Articles

·May 1, 2020·4 min read

Coronavirus infects cells of the intestine: Stool samples could be used to test for virus

SARS-CoV-2, the virus that causes COVID-19, can infect intestinal cells and multiple in the gastrointestinal system. When researchers added SARS-CoV-2 to intestinal organoids, they noticed rapid infection. Researchers say in addition to nasal and throat swabs, rectal swabs and stool samples could be key for coronavirus testing.

Featured Neuroscience Open Neuroscience Articles

·April 29, 2020·2 min read

Tobacco smoking increases lung entry points for COVID-19

Smoking remodels the gene expression of lung cells so that the ACE2 gene is more highly expressed in goblet cells. The effects of smoking on ACE2 pulmonary expression indicates an increase in the overall entry points for coronavirus and increases the risk for viral binding and entry of COVID-19 into the lungs.

Featured Neuroscience Open Neuroscience Articles

·June 24, 2020·5 min read

Statin use is linked to lower death rate in hospitalized COVID-19 patients

Cholesterol-lowering statins show promise for the treatment of severe coronavirus infections. Statins lowered the death rate and decreased the need for mechanical ventilation in patients hospitalized for severe COVID-19.

Featured Genetics Neurology Neuroscience

·May 26, 2020·2 min read

Researchers flag similarities between COVID-19 deaths and severe rheumatic illnesses

After natural killer immune cells kill virus-infected cells, T and B immune cells produce cytokines. This makes the immune reaction stronger and results in the cytokine storm associated with severe COVID-19 infection.

Featured Neuroscience Open Neuroscience Articles

·May 20, 2020·3 min read

COVID-19 cytokine storm: Possible mechanism for the deadly respiratory syndrome

SARS-CoV-2, the virus responsible for COVID-19, enters human cells by attaching to ACE2 and utilizing TMPRSS2. Drugs that block ACE2 or inhibit the enzyme could help treat the coronavirus, but only during early infection. As the infection progresses, SARS-CoV-2 becomes engulfed in human cells, reducing the number of ACE2 receptors on a cell and leading to an increase of angiotensin II in the blood. Angiotensin II triggers an inflammatory pathway, providing a positive feedback cycle, named IL-6 amplifier, resulting in excessive immune activation and the cytokine storm associated with severe COVID-19.

This shows covid 19 with a block on the spike

Featured Neuroscience

·March 27, 2020·6 min read

An experimental peptide could block Covid-19

MIT researchers have identified a protein fragment that may inhibit COVID-19's ability to enter human lung cells. The new peptide can bind to the viral protein and potentially disarm it.

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ACE2

ACE inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19

Exploring why some COVID-19 patients lose their sense of smell

Smokers more likely to express ACE2 protein that coronavirus uses to enter human cells

How COVID-19 Is Likely to Impact the Brain

COVID-19 study shows that men have over double the death rate of women

Coronavirus receptor abundantly expressed in certain progenitor cells

Coronavirus infects cells of the intestine: Stool samples could be used to test for virus

Tobacco smoking increases lung entry points for COVID-19

Statin use is linked to lower death rate in hospitalized COVID-19 patients

Researchers flag similarities between COVID-19 deaths and severe rheumatic illnesses

COVID-19 cytokine storm: Possible mechanism for the deadly respiratory syndrome

An experimental peptide could block Covid-19

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