Researchers suggest the ApoE gene could be a promising new target for therapeutic approaches for Alzheimer's disease.
In fruit fly models, an ABCA1 agonist can restore specific alterations of neuroprotective mechanisms associated with a genetic predisposition to Alzheimer's disease.
Researchers have identified two new genes, ATP8B4 and ABCA1, that are implicated in Alzheimer's disease. The genes impact the brain's immune system and cholesterol processing, leading to an increased risk of developing Alzheimer's disease.
