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new cluprit alzheimers public

This image is a photo of a plastinated Alzheimer's brain.

Researchers found that, in Alzheimer’s and Down Syndrome, βCTF forms more rapidly on endosomes triggering a molecular pathway leading to loss of neurons involved with memory. The researchers discovered APPL1, a protein unrelated to amyloid precursor protein (APP) despite its similar acronym, directly links βCTF to a second protein, rab5, known to activate the molecular chain of events leading to neurodegeneration. Image is for illustrative purposes only.

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