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          antidepressants

          This shows a scale, a pill and mushrooms.
          FeaturedNeurosciencePsychology
          ·March 18, 2026·9 min read

          Psychedelics Match, But Don’t Beat, Traditional Antidepressants

          New research reveals that the perceived advantage of psychedelics over antidepressants disappears when the "knowledge of treatment" factor is equalized.
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          This shows DNA and a fetus.
          FeaturedNeurosciencePsychology
          ·February 13, 2026·8 min read

          Antidepressants May Safeguard Against Preterm Birth Risks

          Does treating depression with antidepressants during pregnancy harm the baby? A massive new study reveals that while SSRIs increase gestational diabetes risk, they also protect against preterm birth.
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          This shows a woman, hearts, a brain, and brain waves.
          FeaturedNeurosciencePsychology
          ·October 13, 2025·6 min read

          EEG Test May Reveal Who Loses Libido on Antidepressants

          A new study reveals that serotonin levels in the brain, measured using a simple EEG-based test, can predict who will experience sexual side effects from SSRI antidepressants. Researchers found that people with higher serotonin activity before treatment were significantly more likely to have difficulty reaching orgasm during antidepressant use.
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          This shows a brain and DNA.
          FeaturedGeneticsNeurosciencePsychology
          ·July 19, 2025·7 min read

          Why Antidepressants Work Better for Some

          A meta-analysis of gene expression data from humans and rodents reveals key biological pathways influencing response to the antidepressant fluoxetine. The study highlights the role of immune-related pathways, including toll-like receptor signaling, and neural signal transduction mechanisms in distinguishing responders from non-responders.
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          This shows a depressed woman.
          FeaturedNeurosciencePsychology
          ·June 6, 2024·4 min read

          How Antidepressants Treat Major Depression

          Researchers have developed a new framework explaining how antidepressants, like SSRIs, treat major depressive disorder (MDD) by restoring brain connectivity rather than correcting a serotonin imbalance. Their findings emphasize the continued importance of these medications despite shifting public opinion. This new understanding could improve patient-clinician conversations about depression treatment.
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          This shows a head and pills.
          FeaturedNeurosciencePsychology
          ·May 30, 2024·6 min read

          AI Tool Matches Patients to Effective Antidepressants Faster

          Researchers developed an AI-based tool, MeAgainMeds.com, to help match patients with the most effective antidepressants based on their medical history. This free website aims to reduce the trial-and-error process in finding the right medication, improving patient outcomes.
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          This shows a brain scan.
          FeaturedNeurosciencePsychology
          ·February 16, 2024·3 min read

          Antidepressants Impact Brain Development

          Using antidepressants during pregnancy, specifically fluoxetine (found in Prozac and Sarafem), can significantly affect a child's brain development, particularly in the prefrontal cortex, potentially increasing the risk of mental health disorders later in life. The research highlights how serotonin, boosted by fluoxetine, directly impacts the development of synaptic connections in the prefrontal cortex, a critical area for high-order cognitive functions.
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          This shows a woman running.
          FeaturedNeurosciencePsychology
          ·October 7, 2023·6 min read

          Running Parallels Antidepressants in Reducing Depression

          Researchers offered 141 patients with anxiety and/or depression a choice between 16 weeks of SSRIs (antidepressants) or group running therapy, revealing both options approximately equally benefited mental health. However, physical health improvements—including weight, waist circumference, and cardiovascular function—were notably observed in the running group, despite a higher dropout rate.
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          This shows a head covered in pills.
          FeaturedNeurosciencePsychology
          ·September 13, 2023·4 min read

          Antidepressants May Boost Memory Function and Reduce Negative Memories

          A new study delves into the relationship between antidepressants and memory dynamics. The study reveals that these drugs may dampen negative memories and bolster overall memory function in individuals with depression.
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          This shows a woman holding a pill
          FeaturedNeuroscience
          ·May 4, 2023·5 min read

          Reproductive Aging May Be Slowed by SSRI Antidepressants

          Selective serotonin reuptake inhibitors (SSRIs) commonly used to treat depression and anxiety can improve the quality of aging females' egg cells in roundworms and fruit flies. The study found that the exposure to SSRIs decreased embryonic death and chromosomal abnormalities in surviving offspring. The researchers said that these findings could lead to new opportunities to explore pharmacological interventions that could combat infertility issues in humans by improving egg quality and delaying the onset of reproductive aging.
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          This shows pills and scrabble tiles reading Help
          FeaturedNeurosciencePsychology
          ·February 28, 2023·5 min read

          Considering Going Off Antidepressants? Here’s What to Think About First

          During the COVID-19 pandemic, there has been an uptick in the use of antidepressant medications to combat symptoms of depression. Researchers discuss the impact of antidepressant usage and provide guidelines for safe and effective withdrawal from antidepressant medications.
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          This shows a drawing of a person holding the back in pain
          FeaturedNeurologyNeuroscienceOpen Neuroscience ArticlesPain
          ·February 2, 2023·7 min read

          Antidepressants Use for Chronic Pain on the Rise, but Are They Effective?

          SNRI antidepressants appear to be effective in the treatment of a range of pain conditions including neuropathic pain, fibromyalgia, and postoperative pain. Tricyclic antidepressants may not be effective in the treatment of pain.
          Read More
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          A 3D digital rendering showing a developing fetal brain connected by glowing neural pathways and floating DNA strands, surrounded by subtle immune cells.

          How Severe Illness During Pregnancy Alters Fetal Brain Development

          A 3D digital illustration of a human brain side-by-side comparison, highlighting the language centers glowing brightly and equally in both a younger and older brain, while executive function areas are dimmed in the older brain.

          Aging Brains Maintain Robust Language Networks Despite Cognitive Decline

          Rejuvenation of Microglia by Youth Protein TIMP2 in the Aging Brain

          Youth Protein TIMP2 Restores Immune Function in the Aging Brain

          A multi-panel documentary photo. Left: A Black man sits alone on a locker room bench with his head down. Center: A Latino man sits withdrawn at a family kitchen table. Right: A White man looks thoughtfully at wellness pamphlets in a public waiting area. All convey isolation.

          Shame, Stigma, and Culture Prevent Male Domestic Violence Survivors From Seeking Help

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