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Genetics

Genetics articles related to neuroscience research will be listed here.

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Pain in the Potassium Channels

The removal of a certain class of potassium channels from the surface of nociceptors is believed to be a key factor in inflammatory pain signaling. Using gene interference to reduce the expression of these specific potassium channels on nociceptors, researchers were able to produce hyperexcitability in nociceptors resembling that seen in inflammatory pain signaling.

Early Life Stresses Could Have Lasting Effects On GAD1 Gene

Neuroscience research published in September's Journal of Neuroscience suggests early life stresses may modify the GAD1 gene, which controls the production of GABA. Through their research on rats, researchers were able to note that those who experienced a lack of affection showed an obstruction within the DNA which controls the GAD1 gene. As it is believed that GABA deficits might be apparent within schizophrenic patients, researchers propose that the modification of GAD1 might determine a child's predisposition to mental illness.

Carbonated Drinks Affect Pain Sensors In Nasal Cavity

Neuroscientists at USC have discovered that carbonated drinks set off the same pain sensors in the nasal cavity as mustard, albeit at a lower intensity. During experimentation, researchers flowed carbonated saline over a dish containing nerve cells taken from the sensory circuits in the nose and mouth. They discovered that the gas activated a specific cell which serve as general pain sensors and expresses the TRPA1 gene.