New Candidate Drug Stops Cancer Cells and Regenerates Nerve Cells
Scientists have developed a small-molecule-inhibiting drug that in early laboratory cell tests stopped breast cancer cells from spreading and also promoted the growth of early nerve cells called neurites. Researchers from Cincinnati Children’s Hospital Medical Center report their findings online June 21 in Chemistry & Biology. The scientists named their lead drug candidate “Rhosin” and [...]
Proposed Drug May Reverse Huntington’s Disease Symptoms
Single treatment produces long-term improvement in animal models. With a single drug treatment, researchers at the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine can silence the mutated gene responsible for Huntington’s disease, slowing and partially reversing progression of the fatal neurodegenerative disorder in animal models. The findings [...]
Genetic Markers – Hope for New Brain Tumor Treatments
Researchers at The University of Nottingham have identified three sets of genetic markers that could potentially pave the way for new diagnostic tools for a deadly type of brain tumor that mainly targets children. The study, published in the latest edition of the prestigious journal Lancet Oncology, was led by Professor Richard Grundy at the [...]
Researchers Determine Pathway for Origin of Most Common Form of Brain and Spinal Cord Tumor
Johns Hopkins scientists hope discovery will drive drug treatments. Johns Hopkins researchers say they have discovered one of the most important cellular mechanisms driving the growth and progression of meningioma, the most common form of brain and spinal cord tumor. A report on the discovery, published in the journal Molecular Cancer Research, could lead the way [...]
Wisconsin Research Team Reveals Novel Way to Treat Drug-Resistant Brain Tumor Cells
New research from the University of Wisconsin-Madison explains why the incurable brain cancer, glioblastoma multiforme (GBM), is highly resistant to current chemotherapies. The study, from the brain-tumor research lab of Dr. John Kuo,assistant professor of neurological surgery and human oncology at UW School of Medicine and Public Health, also reports success for a combination therapy that [...]
Transplanted Gene-Modified Blood Stem Cells Protect Brain Cancer Patients from Toxic Side Effects of Chemotherapy
Study is first to show feasibility and efficacy of a new use for autologous stem cell transplant. For the first time, scientists at Fred Hutchinson Cancer Research Center have transplanted brain cancer patients’ own gene-modified blood stem cells in order to protect their bone marrow against the toxic side effects of chemotherapy. Initial results of [...]
Dental X-Rays Linked to Common Brain Tumor
Meningioma, the most common primary brain tumor in the United States, accounts for about 33 percent of all primary brain tumors. The most consistently identified environmental risk factor for meningioma is exposure to ionizing radiation. In the largest study of its kind, researchers from Brigham and Women’s Hospital (BWH), Yale University School of Medicine, Duke [...]
Researchers Use Nanoparticles, Magnetic Current to Damage Cancerous Cells in Mice
Using nanoparticles and alternating magnetic fields, University of Georgia scientists have found that head and neck cancerous tumor cells in mice can be killed in half an hour without harming healthy cells. The findings, published recently in the journal Theranostics, mark the first time to the researchers’ knowledge this cancer type has been treated using [...]
Scientists Develop First Snap Shot of Tiny Brain Tumors
Cancer Research UK scientists have developed a technique they believe could be used to detect tiny secondary tumors in the brain, a process that is currently impossible, according to research published in PNAS, Monday. The scientists at Cancer Research UK’s Gray Institute for Radiation Oncology and Biology at the University of Oxford showed that a [...]
Altered Gene Linked to Fatal Neuroblastoma in Adolescents, Young Adults
Researchers have identified the first gene mutation associated with a chronic and often fatal form of neuroblastoma that typically strikes adolescents and young adults. The finding provides the first clue about the genetic basis of the long-recognized but poorly understood link between treatment outcome and age at diagnosis. The study involved 104 infants, children and [...]
