FeaturedNeurologyNeuroscience·August 18, 2021·5 min readKey Mechanisms Behind Synapse Degeneration in Alzheimer’s Brain DiscoveredStudy identifies the main components driving amyloid beta-associated synaptic degeneration.Read More
Brain CancerFeaturedGeneticsNeurologyOpen Neuroscience Articles·August 28, 2020·3 min readMaking Brain Cancers in Children Respond Better to TreatmentA small molecular compound has been discovered that can activate the Wnt pathway in non-Wnt subtypes of medulloblastoma brain cancer, making tumors more responsive to therapies.Read More
FeaturedGeneticsNeuroscienceNeuroscience VideosOpen Neuroscience Articles·August 29, 2019·4 min readHuman developmental clock mimicked in a dishThe human development 'clock in a dish' opens up new avenues for research and provides a way to replicate developmental disorders.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·July 25, 2019·4 min readTo become, or not to become… a neuronBcl6 acts as a driver of neurogenic transition by directly silencing a selection of genes that belong to multiple extrinsic pathways promoting self-renewal. Bcl6 is only expressed in specific subsets of neurons and progenitor cells during brain development.Read More
FeaturedNeurology·October 30, 2018·2 min readHow Salt Can Trigger Inflammation in Multiple SclerosisA new study reports salt could be a possible trigger for inflammation in multiple sclerosis. Researchers report cells in a high salt environment show activation of the beta catenin/Wnt signaling pathway, a pathway previously implicated in disrupting regulatory T cells and triggering inflammation.Read More
FeaturedNeuroscience·June 23, 2018·4 min readResearchers Solve the Case of the Missing SubplateA new study reveals subplate cells may not simply disappear, they may, instead, be migrating to different levels of the cortex. In essence, subplate cells may become part of the cerebral cortex.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·December 15, 2017·4 min readTo Sleep or Not to Sleep: The Complex Genetic Network Behind Sleep DurationNIH researchers have identified a set of genes they believe could explain why some people need more, or less, sleep that others. The findings could help to develop new treatments for a variety of sleep disorders from insomnia to narcolepsy.Read More
AutismFeaturedNeuroscienceOpen Neuroscience Articles·November 7, 2017·5 min readLending Late Neurons a Helping HandDelayed neural migration in fetuses may cause behavioral disorders similar to autism, researchers report.Read More
FeaturedGeneticsNeurologyNeuroscienceOpen Neuroscience Articles·April 4, 2017·4 min readMini Brains From the Petri DishResearchers converted skin cells from patients with a rare congenital brain defect into pluripotent stem cells to generate brain organoids.Read More
FeaturedGeneticsPsychology·October 22, 2016·7 min readGene Links Risk of Psychiatric Disease to Reduced Synapse NumbersAccording to researchers, a mutation in a gene associated with brain development may dispose people to various psychiatric illnesses as it reduces synapse numbers. Lithium may help to restore some of the synapses.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesVisual Neuroscience·September 28, 2016·2 min readNew Insight into Eye DiseaseResearchers transfer genes into muller glial cells to activate stem cells properties and cause them to reproduce.Read More
Brain CancerFeatured·August 8, 2015·4 min readChildhood Brain Cancer Can be Classified NoninvasivelyThree subgroups of medulloblastoma brain cancer can be identified non-invasively using MRS neuroimaging technology.Read More