A new study aimed to determine which children are at elevated risk for self-harm events. The study identified four distinct profiles of psychiatric comorbidity in children and adolescents with varying levels of risk for a serious self-harm event. The four profiles can be used to better inform clinical decision-making by providing a better assessment of the overall risk of self-harm, according to the study. Further investigation is needed to validate these risk profiles in larger populations and develop prognostic and clinical decision support applications that provide real-time risk assessments for providers.