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regenerative medicine

A skull is shown with an electrode on it.

·October 16, 2012·3 min read

Less Invasive Method of Brain Stimulation Helps Patients with Parkinson’s Disease

Electrical stimulation using extradural electrodes—placed underneath the skull but not implanted in the brain, is a safe approach with meaningful benefits for patients with Parkinson's disease according to new research.

An image of fly spinal cord equivalent is shown.

Featured Neuroscience

·October 11, 2012·6 min read

Novel Mechanisms Underlying Major Childhood Neuromuscular Disease Identified

A study suggests that spinal muscular atrophy (SMA), a genetic neuromuscular disease in infants and children, results primarily from motor circuit dysfunction, not motor neuron or muscle cell dysfunction, as is commonly thought. In a second study, the researchers identified the molecular pathway in SMA that leads to problems with motor function.

Featured Neurology

·October 4, 2012·3 min read

A Molecular Scissor Related to Alzheimer’s Disease

An international research team revealed the atomic‐level structure of the human peptidase enzyme meprin β (beta).

Featured Neurology

·October 3, 2012·3 min read

Drug Reverses Abnormal Brain Function in Rett Syndrome Mice

in a mouse model of Rett syndrome, researchers were able to reverse abnormalities in brain activity and improve neurological function by treating animals with an FDA-approved anesthesia drug, ketamine.

Featured Neurology

·October 2, 2012·2 min read

New Research Model to Aid Search for Degenerative Disease Cures

Efforts to treat disorders like Lou Gehrig’s disease, Paget’s disease, inclusion body myopathy and dementia will receive a considerable boost from a new research model created by UC Irvine scientists.

Scientists in front of computer monitors examine microscope images showing the growth of axons.

Featured Neuroscience

·October 2, 2012·4 min read

Study Suggests Immune System Can Boost Regeneration of Peripheral Nerves

Research seeks the 'master knob' to turn on nerve repair. Modulating immune response to injury could accelerate the regeneration of severed peripheral nerves, a new study in an animal model has found. By altering activity of the macrophage cells that respond to injuries, researchers dramatically increased the rate at which nerve processes regrew.

A patient with Myasthenia Gravis is shown.

Featured Neurology

·October 1, 2012·3 min read

Researchers Halt Autoimmune Disease Myasthenia Gravis in Mice

Working with mice, Johns Hopkins researchers say they have developed a gene-based therapy to stop the rodent equivalent of the autoimmune disease myasthenia gravis by specifically targeting the destructive immune response the disorder triggers in the body.

Autism Featured Neurology

·September 14, 2012·2 min read

Disorder of Neural Circuits in Autism Mouse Model is Reversible

Scientists have now identified a specific dysfunction in neuronal circuits that is caused by autism. The scientists also report about their success in reversing these neuronal changes in mouse models.

Electrophysiology Featured Neuroscience

·September 14, 2012·3 min read

Scientists Use Prosthetic Device to Restore and Improve Impaired Decision Making Ability in Animals

Scientists used an electronic prosthetic system to tap into existing circuitry in the brain at the cellular level and record the firing patterns of multiple neurons in the prefrontal cortex, the part of the brain involved in decision-making. They then “played” that recording back to the same brain area to electrically stimulate decision-based neural activity. Not only did it restore function, in some cases, it also improved it.

Featured Genetics Neurology

·September 13, 2012·3 min read

Neural Stem Cells Regenerate Axons in Severe Spinal Cord Injury

Researchers were able to regenerate an astonishing degree of axonal growth at the site of severe spinal cord injury in rats. Results were then replicated using two human stem cell lines, one already in human trials for ALS. “We obtained the exact results using human cells as we had in the rat cells,” said Tuszynski.

Featured Neurology

·September 10, 2012·3 min read

Her Vision is 20/20, But She Can’t Make Sense of What She Sees

A rare and baffling neurological disorder called Bálint syndrome, which badly impairs a patient's ability to make sense of what he or she sees is discussed. The article describes, in novelistic detail, the difficult adjustments two patients have had to make in their lives.

Featured Neurology Open Neuroscience Articles

·August 31, 2012·5 min read

Researchers Identify Potential New Approach for Improving Quality of Life for ALS Patients

By increasing the signaling activity of a protein called muscle skeletal receptor tyrosine-protein kinase (MuSK), researchers were able to keep nerve cells attached to muscle longer into the progression of the disease in a mouse model of ALS.

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regenerative medicine

Less Invasive Method of Brain Stimulation Helps Patients with Parkinson’s Disease

Novel Mechanisms Underlying Major Childhood Neuromuscular Disease Identified

A Molecular Scissor Related to Alzheimer’s Disease

Drug Reverses Abnormal Brain Function in Rett Syndrome Mice

New Research Model to Aid Search for Degenerative Disease Cures

Study Suggests Immune System Can Boost Regeneration of Peripheral Nerves

Researchers Halt Autoimmune Disease Myasthenia Gravis in Mice

Disorder of Neural Circuits in Autism Mouse Model is Reversible

Scientists Use Prosthetic Device to Restore and Improve Impaired Decision Making Ability in Animals

Neural Stem Cells Regenerate Axons in Severe Spinal Cord Injury

Her Vision is 20/20, But She Can’t Make Sense of What She Sees

Researchers Identify Potential New Approach for Improving Quality of Life for ALS Patients

Bipolar Disorder Linked to Less Efficient Brain Wiring Networks

Uninherited Parental Genes Shape Child Development

Daily Activity and Positive Mood Form a Continuous Loop

Father’s Pre-Conception Drinking Damages Offspring Mitochondria

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