Researchers use induced pluripotent stem cells to advance disease-in-a-dish modeling of ataxia telangiectasia, a rare genetic disorder associated with progressive loss of function in the cerebellum. Their discovery shows the positive effects of drugs that may lead to effective new treatments for the neurodegenerative disease.
Adapting two dimensional culture methods to grow 3-D neuron structures from induced pluripotent stem cells, researchers may be able to model and study neurodegenerative disorders such as Alzheimer’s disease.
Researchers transplanted neural cells, derived from adult skin cells, into monkeys; where they developed into several different types of brain cells. The research could eventually help provide new treatment avenues for patients with a wide range of neurological diseases.
Researchers from the University of Minnesota’s Lillehei Heart Institute have effectively treated muscular dystrophy in mice using human stem cells derived from a new process that – for the first time – makes the production of human muscle cells from stem cells efficient and effective. The research, published today in Cell Stem Cell, outlines the strategy [...]