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Genetics

New Gene Variants Found to Raise Risk of Neuroblastoma and Influence Tumor Progression

Researchers have discovered two gene variants that raise the risk of the pediatric cancer neuroblastoma. This is the first study to link known cancer-related genes HACE1 and LIN28B to neuroblastoma. The study broadens understanding of how gene changes may make a child susceptible to this early childhood cancer, as well as causing a tumor to progress.... Read More...

Astrocytes Control the Generation of New Neurons from Neural Stem Cells

Neuroscience researchers show how astrocytes control the generation of new neurons in the brain. “In the brain, astrocytes control how many new neurons are formed from neural stem cells and survive to integrate into the existing neuronal networks. Astrocytes do this by secreting specific molecules but also by much less understood direct cell-cell interactions with stem cells”, says Prof. Milos Pekny.... Read More...