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Genetics

Featured Genetics Neurology Neuroscience

·July 1, 2026·12 min read

Optogenetics Restores Motor Learning in Huntington’s

Optogenetically activating underactive VIP inhibitory neurons in the motor cortex completely restores normal circuit activity and motor learning in Huntington’s disease models, with therapeutic benefits persisting long after stimulation ends.

Featured Neuroscience

·June 30, 2026·11 min read

Hand Dominance Is Driven by Practice, Not Birth

The skill gap between our dominant and non-dominant hands is not innate, but rather an emergent consequence of a lifetime of asymmetrical practice that manifests exclusively during tool use.

Featured Genetics Neuroscience Visual Neuroscience

·June 30, 2026·12 min read

Researchers Grow Rare Eye Vessel Cells to Halt Vision Loss

A new study demonstrates the first successful generation of retinal endothelial cells from induced pluripotent stem cells (iPSCs). When tested in vitro, the cells accurately modeled the tissue degradation of diabetic retinopathy, and when injected in vivo, they successfully integrated to regenerate damaged retinal blood vessels and restore function.

Autism Featured Genetics Neuroscience

·June 29, 2026·9 min read

Nanosensor Separates Autism From Intellectual Disability

Scientists demonstrates that a carbon-fiber nanosensor can differentiate Autism Spectrum Disorder from Intellectual Disability by measuring real-time nitric oxide production in undifferentiated patient stem cells, even when both conditions share identical genetic mutations.

Featured Genetics Neurology Neuroscience

·June 29, 2026·9 min read

Brain Tissue Patterns and Genetics Drive MS Progression

A comprehensive study of 287 MS brain tissue donors from the Netherlands Brain Bank demonstrates that multiple sclerosis progression variability is driven by specific pathological features, such as broad rim lesions and myelin repair failures, which are directly modulated by an individual's genetic background.

Featured Genetics Neuroscience

·June 29, 2026·12 min read

Arthritis Drug Found to Reduce Excessive Alcohol Use

An FDA-approved rheumatoid arthritis drug targeting the IL-6 receptor significantly reduces excessive alcohol consumption in alcohol-dependent female mice. The treatment functions by blocking neuroinflammatory pathways that suppress the GABAergic braking system in the central amygdala, a mechanism corroborated by elevated IL-6 expression found in postmortem human AUD brain tissue.

Featured Genetics Neurology Neuroscience

·June 29, 2026·12 min read

Arc Protein Found to Spread Toxic Tau in Alzheimer’s

The native brain protein Arc mediates the intercellular transmission of toxic Tau via extracellular vesicles in Alzheimer's disease. While Arc helps sick neurons survive longer by expelling toxic Tau aggregates, it simultaneously promotes the spread of pathology to healthy cells, identifying the extracellular space as a prime "mid-flight" therapeutic target.

Brain Cancer Featured Genetics Neurology Neuroscience

·June 26, 2026·12 min read

Overcoming Endothelial Sorting to Cure Glioblastoma

Researchers present a shift in neuro-nanomedicine, reframing the "protein corona", the layer of blood proteins that coat nanoparticles, as a programmable, five-stage navigation interface capable of guiding therapeutics across the blood-brain barrier via receptor-mediated transcytosis.

Featured Genetics Neuroscience

·June 26, 2026·14 min read

NANOG Gene Guides Embryonic Development

Researchers utilized ultra-precise base editing to alter a single nucleotide in human embryos, demonstrating that the NANOG gene is uniquely required to form the body-building epiblast layer, while revealing key developmental differences between humans and mice.

Featured Genetics Neurology Neuroscience

·June 25, 2026·9 min read

Immune Receptor TREM-1 Amplifies Neuroinflammation

A new study outlines the biological role of TREM-1 as a master upstream amplifier of innate immunity, highlighting its synergy with Toll-like receptors and its emergence as a high-value therapeutic target for stopping acute sepsis, inflammatory arthritis, and microglial-driven neurodegeneration.

This shows cells undergoing karyoptosis.

Featured Neurology Neuroscience

·June 25, 2026·10 min read

New Form of Cell Death Discovered in Alzheimer’s

Researchers identified a new form of programmed cell death called karyoptosis, driven by the interaction of p38 MAP kinase and LaminB1, which causes nuclear disintegration in 35% of Alzheimer's frontal cortex neurons.

Autism Featured Genetics Neuroscience

·June 24, 2026·10 min read

Dogs May Bridge the Autism Drug Discovery Gap

Shank3 mutant laboratory Beagles could bridge the 90% failure gap in autism drug development, as their uniquely co-evolved social architecture allows them to mirror human-like social withdrawal, gaze aversion, and sensory changes far better than rodent models.

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Genetics

Optogenetics Restores Motor Learning in Huntington’s

Hand Dominance Is Driven by Practice, Not Birth

Researchers Grow Rare Eye Vessel Cells to Halt Vision Loss

Nanosensor Separates Autism From Intellectual Disability

Brain Tissue Patterns and Genetics Drive MS Progression

Arthritis Drug Found to Reduce Excessive Alcohol Use

Arc Protein Found to Spread Toxic Tau in Alzheimer’s

Overcoming Endothelial Sorting to Cure Glioblastoma

NANOG Gene Guides Embryonic Development

Immune Receptor TREM-1 Amplifies Neuroinflammation

New Form of Cell Death Discovered in Alzheimer’s

Dogs May Bridge the Autism Drug Discovery Gap

Study Supports and Expands the Primate Brain Lag Hypothesis

Slow Maternal Response Time Linked to ADHD in Kids

The Neural Circuit Behind Flexible Thinking

Acetaminophen Cleared of Autism and ADHD Pregnancy Risks

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