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Alzheimer’s disease

·December 10, 2025·8 min read

AI Turns Simple EEG Scans Into Accurate Dementia Detectors

New research shows that deep learning can use EEG signals to distinguish Alzheimer’s disease from frontotemporal dementia with high accuracy. By analyzing both the timing and frequency of brain activity, the model uncovered distinct patterns: broader disruption across multiple regions in Alzheimer’s and more localized frontal and temporal changes in frontotemporal dementia.

Featured Genetics Neurology Neuroscience

·December 6, 2025·7 min read

Blocking a Key Protein Greatly Reduces Alzheimer’s Damage

New findings show that removing Centaurin-α1, a protein elevated in Alzheimer’s disease, significantly reduces inflammation, plaque buildup, and cognitive deficits in a well-established mouse model. Eliminating this protein normalized several brain pathways, protected neural connections in the hippocampus, and improved spatial learning.

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Featured Neurology Neuroscience

·December 5, 2025·6 min read

Microplastics Accelerate Alzheimer’s and Parkinson’s Damage

A new review highlights five major ways microplastics can harm the brain, raising concerns that they may worsen neurodegenerative diseases like Alzheimer’s and Parkinson’s. These tiny particles can trigger inflammation, disrupt the blood–brain barrier, generate oxidative stress, impair mitochondria, and damage neurons.

Featured Neurology Neuroscience

·December 2, 2025·6 min read

Obesity Speeds Alzheimer’s Biomarker by Up to 95 Percent

New longitudinal research shows that Alzheimer’s disease blood biomarkers rise up to 95 percent faster in people with obesity than in those without. While baseline tests initially appeared lower due to blood dilution, long-term tracking revealed a significantly accelerated buildup of neurodegeneration and amyloid pathology.

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Neuroscience

·December 2, 2025·12 min read

Shingles Vaccine Linked to 20% Lower Dementia Risk

A large population analysis found that older adults who received the shingles vaccine were significantly less likely to develop dementia over the following seven years. The study exploited a rare age-based rollout policy that closely mimicked a randomized trial, allowing researchers to isolate the vaccine’s true effect.

Featured Genetics Neurology Neuroscience

·November 21, 2025·6 min read

Genetics Plus Heart Health Markers Sharpen Dementia Risk

New research shows that dementia risk is best predicted by combining genetic vulnerability with cardiovascular disease markers, revealing a more precise and actionable way to identify who is most likely to develop the condition. While genes such as APOE4 and family history contribute heavily, equally powerful are modifiable factors like hypertension, obesity, and diabetes.

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Featured Neurology Neuroscience

·November 21, 2025·6 min read

Supplement Shows Promise in Blocking Amyloid in Alzheimer’s

A new study shows that oral arginine, a naturally occurring amino acid, can significantly suppress amyloid-β aggregation in Alzheimer’s disease models. Researchers found that arginine not only prevented Aβ42 from clumping but also reduced plaques and inflammation in mouse and fruit fly models carrying Alzheimer’s-related mutations.

Featured Neurology Neuroscience

·November 19, 2025·7 min read

Lithium Fails to Slow Cognitive Decline in Alzheimer’s

A new meta-analysis of six randomized controlled trials shows that lithium supplementation does not significantly slow cognitive decline in people with mild cognitive impairment or Alzheimer’s disease. While preclinical evidence suggests lithium supports resilience against amyloid and tau pathology, these benefits failed to translate to clinical outcomes using traditional lithium salts.

Featured Neurology Neuroscience

·November 12, 2025·5 min read

Alzheimer’s Drug Reduces Amyloid but Fails to Restore Brain Waste Flow

Researchers found that lecanemab, the Alzheimer’s drug designed to clear amyloid-β plaques, does not improve the brain’s waste clearance system in the short term. In a three-month study using MRI-based DTI-ALPS imaging, scientists observed no measurable recovery in glymphatic function after treatment.

This shows a family and the face of an older woman.

Featured Neurology Neuroscience

·November 10, 2025·7 min read

Why Alzheimer’s Patients Forget Loved Ones

Researchers have discovered that the heartbreaking moment when a person with Alzheimer’s no longer recognizes family may stem from the breakdown of perineuronal nets, protective structures that support social memory. In mice, the loss of these nets erased memory of familiar individuals while sparing object memory, mirroring early human symptoms.

Featured Neurology Neuroscience

·November 5, 2025·6 min read

Your Neighborhood Could Influence Your Risk of Dementia

Researchers found that living in a socioeconomically deprived neighborhood can harm brain health as early as midlife. People from these areas showed more signs of small-vessel brain damage, slower thinking skills, and poorer control of lifestyle factors such as blood pressure, obesity, and sleep.

Featured Neurology Neuroscience

·November 5, 2025·5 min read

Brain’s Immune Cells Found to Protect Against Alzheimer’s Damage

Researchers have uncovered how the brain’s immune cells, called microglia, can act as protectors rather than destroyers in Alzheimer’s disease. By lowering the immune regulator PU.1, microglia began expressing lymphoid-like receptors that reduced inflammation and preserved cognitive function in mouse models.