Protein Involved in DNA Replication, Centrosome Regulation Linked to Dwarfism, Small Brain Size

Protein Involved in DNA Replication, Centrosome Regulation Linked to Dwarfism, Small Brain Size

Research just published by scientists at Cold Spring Harbor Laboratory (CSHL) links gene mutations found in some patients with Meier-Gorlin syndrome (MGS) with specific cellular dysfunctions that are thought to give rise to a particularly extreme version of dwarfism, small brain size, and other manifestations of abnormal growth which generally characterize that rare condition.

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Brains Are Different in People with Highly Superior Autobiographical Memory

Brains Are Different in People with Highly Superior Autobiographical Memory

UC Irvine scientists have discovered intriguing differences in the brains and mental processes of an extraordinary group of people who can effortlessly recall every moment of their lives since about age 10. Research offers the first scientific findings about nearly a dozen people with this highly superior autobiographical memory (HSAM).

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Brain Development is Delayed in Attention-Deficit/Hyperactivity Disorder

Brain Development is Delayed in Attention-Deficit/Hyperactivity Disorder

Researchers found that development of the cortical surface is delayed in frontal brain regions in children with ADHD. The typically developing children attained 50% peak area in the right prefrontal cortex at a mean age of 12.7 years, whereas the ADHD children didn’t reach this peak until 14.6 years of age.

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Connectomics: Mapping the Neural Network Governing Male Roundworm Mating

Connectomics: Mapping the Neural Network Governing Male Roundworm Mating

Researchers determined how the neurons and muscles are connected in a decision-making neural network important for mating in C. elegans. The team also accurately measured the weights of those connections, i.e., an estimate of the strength with which one neuron or muscle communicates with another.

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The Seat of Meta-Consciousness in the Brain

The Seat of Meta-Consciousness in the Brain

Studies of lucid dreamers visualise which centers of the brain become active when we become aware of ourselves. Studies demonstrate that a specific cortical network consisting of the right dorsolateral prefrontal cortex, the frontopolar regions and the precuneus is activated when this lucid consciousness is attained.

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Study Pinpoints a Genetic Cause of Most Lethal Brain Tumor and May Lead to New Treatment

Study Pinpoints a Genetic Cause of Most Lethal Brain Tumor and May Lead to New Treatment

Researchers discovered that some cases of glioblastoma, the most common and aggressive form of primary brain cancer, are caused by the fusion of two adjacent genes. The study also found that drugs that target the protein produced by this genetic aberration can dramatically slow the growth of glioblastomas in mice.

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Controlling Monkey Brains and Behavior With Light

Controlling Monkey Brains and Behavior With Light

Researchers can control the behavior of monkeys by using pulses of blue light to very specifically activate particular brain cells. The findings represent a key advance for optogenetics, a state-of-the-art method for making causal connections between brain activity and behavior. Researchers say that similar light-based mind control could likely also be made to work in humans for therapeutic ends.

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Ion Selectivity in Neuronal Signaling Channels Evolved Twice in Animals

Ion Selectivity in Neuronal Signaling Channels Evolved Twice in Animals

Scientists have now revealed that voltage-gated sodium channels, which are responsible for neuronal signaling in the nerves of animals, evolved twice in higher and lower animals.

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Sum of the Parts? How Our Brains See Men as People and Women as Body Parts

Sum of the Parts? How Our Brains See Men as People and Women as Body Parts

Study finds that both genders process images of men, women differently.

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Cylindrical Cell Structure Parts May Aid in Targeting Diseases Such as Cancer, Alzheimer’s, Parkinson’s

Cylindrical Cell Structure Parts May Aid in Targeting Diseases Such as Cancer, Alzheimer’s, Parkinson’s

The model of microtubule assembly that most people accept shows the individual subunits, dimers of the protein tubulin, just adding to the grow cylinder. But another model indicates that tubulin dimmers first form an open sheet structure that later closes into the cylinder. Xing and his team concluded that their computational study of the models indicate that the second model should be seriously considered for further testing.

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